Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
In the study of bacteria, a longstanding dogma has held that two molecular machines—RNA polymerase, which leads the way in transcribing DNA into RNA, and ribosomes, which bring up the rear translating RNA into proteins—worked ...
Cell & Microbiology
Jul 2, 2026
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Female fertility depends on the successful growth and maturation of eggs (oocytes) within ovarian follicles. Within these follicles, the oocyte is surrounded by granulosa cells that supply nutrients, signaling molecules and ...
Cell & Microbiology
Jul 2, 2026
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Embedded in the boundary between the inside and outside of each cell are membrane proteins. They act as first responders by sensing signals, regulating which molecules enter and leave the cell, and enabling cells to quickly ...
Cell & Microbiology
Jul 2, 2026
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Inside every cell are lipid molecules that make up cellular membranes, helping organelles communicate and respond to stress. Researchers have struggled to observe lipids in action because current detection tools lack sufficient ...
Cell & Microbiology
Jul 2, 2026
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While many of life's mysteries remain unsolved, every biologist can describe the basic processes performed by a living organism, including energy use, reproduction, growth and development. While these characteristics can ...
Cell & Microbiology
Jul 1, 2026
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Every time a cell copies its DNA, parts of the genome are exposed and vulnerable to damage or errors. Molecular biologist Simon Boulton is interested in how cells spot and repair damage to their DNA, and what happens if this ...
Cell & Microbiology
Jun 30, 2026
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The technology at the center of the growing "resolution revolution" has again shown its value to scientists at Yale by revealing the secrets of gum disease.
Cell & Microbiology
Jun 30, 2026
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Researchers have developed a way to program human cells to perform calculations and make autonomous decisions, similar to how computer chips work.
Cell & Microbiology
Jun 30, 2026
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Researchers from the University of Osaka have demonstrated that mitochondrial hyperfusion, when induced by low levels of DRP1 or cellular stress, activates an immune response through the RIG-I–MAVS pathway. Dependent on the ...
Cell & Microbiology
Jun 29, 2026
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A global team has cracked a decades-old mystery, revealing the atomic structures of the molecules in our eyes that allow us to see colors. "To understand how we detect light and perceive colors, we need to know the exact ...
Cell & Microbiology
Jun 26, 2026
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