Page 11: Research news on Biomolecular & subcellular processes

Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.

AI-designed miniproteins switch key cell receptors on and off

G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a living cell. They communicate with nearly every physiological process in our bodies—from the ability ...

Human cells can exchange genomic DNA that alters cell behavior

Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that large pieces of DNA can transfer directly between human cells, and the DNA can persist and change how the recipient ...

Decoding the balance between life-and-death proteins

In every organism, the regulation of cell populations is a constant process. This balance relies on a continuous interplay between "guardian" proteins that promote cell survival and "killer" proteins that trigger programmed ...

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