Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
In the pursuit of solutions to complex global challenges including disease, energy demands, and climate change, scientific researchers, including at MIT, have turned to artificial intelligence, and to quantitative analysis ...
Molecular & Computational biology
Feb 7, 2026
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All life on Earth shares a common ancestor that lived roughly four billion years ago. This so-called "last universal common ancestor" (LUCA) represents the most ancient organism that researchers can study. Previous research ...
Evolution
Feb 5, 2026
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One of the most enduring goals in regenerative medicine is deceptively simple: replace a person's damaged or dying cells with healthy new ones grown in the laboratory.
Biotechnology
Feb 4, 2026
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Gene regulation is far more predictable than previously believed, scientists conclude after developing the deep learning model PARM. This might bring an end to a scientific mystery: how genes know when to switch on or off.
Biotechnology
Feb 4, 2026
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22
An international research team headed by scientists from Nanyang Technological University, Singapore and the Center for Structural Systems Biology and Bernhard-Nocht Institute for Tropical Medicine in Germany has revealed ...
Cell & Microbiology
Feb 2, 2026
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16
Artificial intelligence allows tracing the evolution of genetic control elements in the developing mammalian cerebellum. An international research team led by biologists from Heidelberg University as well as the Vlaams Instituut ...
Evolution
Jan 29, 2026
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49
Last year, a ten-month-old baby in the US was the first person in the world to have their rare genetic disease effectively cured through the use of CRISPR gene editing technology. But the rollout of CRISPR across a wide range ...
Biotechnology
Jan 26, 2026
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52
Researchers at Forschungszentrum Jülich and Heinrich Heine University Düsseldorf have developed a tool that could significantly transform genome research: Helixer identifies genes directly from DNA sequences—without laboratory ...
Molecular & Computational biology
Jan 26, 2026
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16
Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments that can control gene activity in specific cells. These sequences, called cis-regulatory elements ...
Biotechnology
Jan 26, 2026
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23
Engineers at the University of California have developed a new data structure and compression technique that enables the field of pangenomics to handle unprecedented scales of genetic information. The team, led by UC San ...
Biotechnology
Jan 12, 2026
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