Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
Studying gene expression in a cancer patient's cells can help clinical biologists understand the cancer's origin and predict the success of different treatments. But cells are complex and contain many layers, so how the biologist ...
Cell & Microbiology
Feb 25, 2026
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19
A new tool enables biomedical researchers from around the world to quickly see the connections between lipids and proteins inside cells, thanks to a new initiative led by scientists at Oregon Health & Science University. ...
Molecular & Computational biology
Feb 25, 2026
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9
University of Missouri researchers have released the world's largest collection of protein models with quality assessment—a groundbreaking new resource that could accelerate drug development for diseases such as Alzheimer's ...
Biotechnology
Feb 18, 2026
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35
Every living organism has its own genetic "blueprint": the source code for how it grows, functions and reproduces. This blueprint is known as a genome. When scientists sequence a genome, they identify and put in order the ...
Ecology
Feb 17, 2026
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11
Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful compounds. In a new study, MIT chemical engineers have harnessed artificial intelligence to optimize ...
Biotechnology
Feb 17, 2026
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72
Haoyu Cheng, Ph.D., assistant professor of biomedical informatics and data science at Yale School of Medicine, has developed a new algorithm capable of building complete human genomes using standard laboratory technology. ...
Biotechnology
Feb 16, 2026
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100
A new software tool, ovrlpy, improves quality control in spatial transcriptomics, a key technology in biomedical research. Developed by the Berlin Institute of Health at Charité (BIH) in international collaboration, ovrlpy ...
Biotechnology
Feb 10, 2026
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25
Cucumber is an economically important crop worldwide, ranking as the third most-produced vegetable after tomatoes and onions. Yet breeding improved varieties—plants that are more resilient, produce better-shaped fruit, or ...
Plants & Animals
Feb 10, 2026
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21
Scientists at the Department of Energy's Oak Ridge National Laboratory have developed software that reduces the time needed for a key task in the development of custom microbes from a week to just hours. The new tool cracks ...
Biotechnology
Feb 9, 2026
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14
Scientists in the laboratory of Rendong Yang, Ph.D., associate professor of Urology, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more accurately than conventional ...
Biotechnology
Feb 9, 2026
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