Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
Proteins regulate a wide range of biological processes inside and outside cells by binding to specific molecular partners. In recent years, short peptides that can selectively recognize disease-related proteins have attracted ...
Molecular & Computational biology
Jul 16, 2026
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3
Just as this country celebrated its 250th birthday, some geneticists were celebrating America, too. At the end of June, the National Institutes of Health announced its "All of Us" Research Program had become the world's largest ...
Molecular & Computational biology
Jul 15, 2026
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11
Researchers have developed a new computational approach that enables more accurate selection of genes that characterize different cellular states from mRNA-seq data, offering a more interpretable way to analyze complex biological ...
Biotechnology
Jul 15, 2026
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5
Far beneath the surface of the ocean lies the largest and least explored habitat on Earth. The deep sea is cold, dark, highly pressurized—and home to a huge amount of undiscovered life.
Evolution
Jul 12, 2026
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19
For researchers on the hunt for the genetic roots of disease, the cost of deep whole-genome sequencing makes it challenging to conduct large genetic studies involving thousands of participants, which are needed to reveal ...
Molecular & Computational biology
Jul 12, 2026
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83
A new Northwestern Medicine study published in the Proceedings of the National Academy of Sciences has explored the impacts of aging on essential cellular processes, findings that could shape the development of future anti-aging ...
Cell & Microbiology
Jul 9, 2026
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41
Phylo-Plex, a new computational method, has been developed by Wellcome Sanger Institute scientists and their collaborators to allow cost-effective and scalable DNA sequencing of pathogens in laboratories with limited resources. ...
Molecular & Computational biology
Jul 9, 2026
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20
RNA has emerged as one of the most promising molecules in modern medicine, enabling advances from mRNA vaccines and gene therapies to genome editing and synthetic biology. However, designing RNA molecules that reliably fold ...
Biotechnology
Jul 8, 2026
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11
In a paper published in Proceedings of the National Academy of Sciences, researchers from Technion and Tel Aviv University present BetaDescribe, an AI system that translates protein sequences into natural-language descriptions, ...
Biotechnology
Jul 6, 2026
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77
Decades-old hospital samples have helped University of East Anglia (UEA) researchers uncover how a deadly antibiotic-resistant "superbug" quietly tightened its grip across the globe. It lurked in hospital corridors for decades, ...
Evolution
Jul 1, 2026
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204
