A new mechanism for accessing damaged DNA

UV light damages the DNA of skin cells, which can lead to skin cancer. But this process is counteracted by DNA repair machinery, acting as a molecular sunscreen. It has been unclear, however, how repair proteins work on DNA ...

Life in evolution's fast lane

Most living things have a suite of genes dedicated to repairing their DNA, limiting the rate at which their genomes change through time. But scientists at Vanderbilt and University of Wisconsin-Madison have discovered an ...

DNA damage repair—molecular insights

The first line of defense against skin cancer is the ability to repair DNA damage caused by UV light. The XPA protein plays an important role in the repair of certain DNA damage, and mutations in this protein have been implicated ...

Research zooms in on enzyme that repairs DNA damage from UV rays

A research team at the Department of Energy's SLAC National Accelerator Laboratory is using the Linac Coherent Light Source (LCLS) to study an enzyme found in plants, bacteria and some animals that repairs DNA damage caused ...

Low temperature increases risk of DNA damage from UV radiation

Ultraviolet (UV) radiation exposure can cause DNA damage and may be one of the contributing factors in the global amphibian extinction crisis. New research from Prof Craig Franklin and a team of researchers from The University ...

The keys to a major process in DNA repair

Researchers from the Institut Jacques Monod (CNRS/University of Paris Diderot), the Institute of Biology of the Ecole Normale Supérieure (ENS/CNRS/Inserm), and the University of Bristol, have described for the first time ...

Whales feel the (sun)burn

Whales have been shown to increase the pigment in their skin in response to sunshine, just as we get a tan.

Stem cells: Tuning the death sentence

In this week's issue of Science Signaling (22 January, 2013), Danen and colleagues of the Division of Toxicology of LACDR report novel insights into the question how stem cells decide to commit suicide when their DNA is damaged.

Suncreen from the sea

King's College London has entered into an agreement with skincare company Aethic to develop the first sunscreen based on MAA's (mycosporine-like amino acids), produced by coral.

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