The first three-dimensional structure of DHHC proteins—enzymes involved in many cellular processes, including cancer—explains how they function and may offer a blueprint for designing therapeutic drugs. Researchers have ...
Biochemistry
Jan 11, 2018
0
34
Researchers have engineered an artificial protein that may block malignant properties of cancer cells as well as correct certain birth defects.
Biochemistry
Nov 14, 2017
0
27
Immune cells called "killer cells" target bacteria invading the body's cells, but how do they do this so effectively? Bacteria can quickly evolve resistance against antibiotics, yet it seems they have not so readily been ...
Cell & Microbiology
Nov 8, 2017
0
93
A nanoscale antibody first found in camels combined with a protein-degrading molecule is an effective new platform to control protein levels in cells, according to Rice University scientists. The technique could aid fundamental ...
Cell & Microbiology
Oct 30, 2017
0
99
UC San Francisco researchers recently captured exquisite images of a protein caught in the act of binding to a novel therapeutic drug with enough resolution to model how the individual atoms of the protein and drug lined ...
Cell & Microbiology
Oct 27, 2017
1
423
Most drugs work by tinkering with the behavior of proteins. Like meddlesome coworkers, these molecules are designed to latch onto their target proteins and keep them from doing what they need to do.
Biochemistry
Oct 11, 2017
0
59
Researchers have designed a system that rapidly recognises the specific biological molecules that can indicate disease.
Nanomaterials
Sep 19, 2017
0
102
Researchers from North Carolina State University have developed a high-throughput technique that can determine if a chemical has the potential to activate key genes in seconds rather than the typical 24 hours or more. The ...
Analytical Chemistry
Aug 22, 2017
0
5
A novel method to improve the high-yield, high-purity, high-activity purification of complex proteins by 10- to 500-fold has been developed at the University of Alabama at Birmingham.
Biochemistry
Jul 5, 2017
0
5
Scientists at the University of Bath funded by Cancer Research UK have custom-built a molecule which stops breast cancer cells from multiplying in laboratory trials, and hope it will eventually lead to a treatment for the ...
Biochemistry
Jun 22, 2017
0
27
