Researchers at IRB Barcelona, the University of Barcelona (UB), VIMM, and the University of Padua unveil the key role of Mitofusin 2 cellular makeup in interconnecting organelles within cells. The findings are published in ...
Cell & Microbiology
Jun 28, 2023
0
14
A research team led by Prof. Xue Yuanchao from the Institute of Biophysics of the Chinese Academy of Sciences has developed a new method for global profiling of in-situ RNA–RNA contacts associated with a specific RNA-binding ...
Cell & Microbiology
Mar 23, 2023
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82
A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms—including the universally-studied worm C. elegans—have almost the same number of genes.
Biotechnology
Mar 23, 2023
1
133
On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein. This process, known as alternative splicing, allows a single gene to ...
Molecular & Computational biology
Jan 20, 2023
1
168
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona reveal that Srrm3 is a master regulator gene crucial for the development of photoreceptors, cells in the back of the retina which capture and process light, ...
Cell & Microbiology
Jul 13, 2022
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23
Alternative splicing is a fundamental biological process that allows cells to make many different types of mRNAs and proteins from a limited number of genes. For many animals, including humans, it is a feature that is essential ...
Molecular & Computational biology
Apr 13, 2022
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40
Protein-coding genes carry the blueprint for protein production. In higher organisms, however, most of the coding-gene transcripts, or pre-mRNAs, are separated by non-coding sequences called "introns," which must be cut out ...
Molecular & Computational biology
Aug 13, 2021
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551
In an article published in the journal RNA, Karan Bedi, a bioinformatician in Mats Ljungman's lab, Department of Radiation Oncology at the University of Michigan Medical School, investigated the efficiency of splicing across ...
Biotechnology
Jul 9, 2021
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8
Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. A new bioengineered reporter system developed at ...
Cell & Microbiology
Jun 4, 2021
0
12
RNA is the central tenet of molecular biology, the stepping-stone between DNA and proteins.
Biotechnology
Feb 4, 2021
0
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