Lariats are discarded byproducts of RNA splicing, the process by which genetic instructions for making proteins are assembled. A new study has found hundreds more lariats than ever before, yielding new information about how ...
Cell & Microbiology
Jun 17, 2012
0
0
When the human genome was first sequenced, experts predicted they would find about 100,000 genes. The actual number has turned out to be closer to 20,000, just a few thousand more than fruit flies have. The question logically ...
Cell & Microbiology
Dec 31, 2014
107
0
In a recent paper in RNA Biology, researchers show that mitochondria translocate their key RNA methyltransferase enzyme, TRMT1, into host cell nuclei in response to neural activity. This subcellular relocalization of key ...
A tool that has already revolutionized disease research may soon get even better, thanks to an accidental discovery in the bacteria that cause many of the worst cases of meningitis.
Biotechnology
Feb 15, 2018
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377
In a development that could accelerate the discovery of new diagnostics and treatments, researchers at Children's Hospital of Philadelphia (CHOP) have developed a versatile and low-cost technology for targeted sequencing ...
Molecular & Computational biology
Aug 15, 2023
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54
RNA is the key functional component of spliceosomes, molecular machines that control how genes are expressed, report scientists from the University of Chicago online, Nov. 6 in Nature. The discovery establishes that RNA, ...
Cell & Microbiology
Nov 6, 2013
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1
On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein. This process, known as alternative splicing, allows a single gene to ...
Molecular & Computational biology
Jan 20, 2023
1
168
Some three billion base pairs make up the human genome—the floor plan of life. In 2003, the Human Genome Project announced the successful decryption of this code, a tour de force that continues to supply a stream of insights ...
Bio & Medicine
Apr 6, 2014
2
0
A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression. The study was published on line in advance ...
Cell & Microbiology
Nov 10, 2013
0
0
What has spoiled tens upon tens of thousands of fledgling oil palm plants at elite corporate plantations in Malaysia and elsewhere in Southeast Asia over the last three decades? The answer to this problem, which has cost ...
Biotechnology
Sep 9, 2015
3
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