A little-studied factor known as the Little Elongation Complex (LEC) plays a critical and previously unknown role in the transcription of small nuclear RNAs (snRNA), according to a new study led by scientists at the Stowers ...
Cell & Microbiology
Aug 8, 2013
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Most people are familiar with the cell nucleus from grade school biology as a storage compartment for DNA. But the nucleus also contains several distinct structures, called nuclear bodies or domains, whose roles scientists ...
Molecular & Computational biology
Mar 2, 2022
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89
Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!"- signal to read their part of the genomic symphony. ...
Cell & Microbiology
Jul 14, 2011
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Like an impossibly twisted telephone cord, DNA, the molecule that encodes genetic information, also often finds itself twisted into coils. This twisting, called supercoiling, is caused by enzymes that travel along DNA's helical ...
Cell & Microbiology
Jun 28, 2013
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New work by scientists in the U.S. and China shows how a fertilized egg cell, or zygote, hits "reset" so that the newly formed embryo can develop according to its own genetic program. The study was published July 17 in Nature.
Cell & Microbiology
Jul 20, 2023
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34
Every cell in your body carries the same genetic instructions, and yet cells don't accidentally turn into bone inside your heart, and teeth don't grow in your brain. This is thanks to systems of precise control over the expression ...
Biochemistry
Sep 15, 2015
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116
Deep inside your cells, DNA provides the instructions to produce proteins, the essential molecules that grow and maintain your body.
Cell & Microbiology
Nov 17, 2020
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1720
The quest to better understand how genomic information is read has taken a new step forward, thanks to pioneering new research.
Molecular & Computational biology
Dec 6, 2019
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69
So much of what happens inside cells to preserve health or cause disease is so small or time-sensitive that researchers are just now getting glimpses of the complexities unfolding in us every minute of the day. UNC School ...
Cell & Microbiology
Aug 24, 2017
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218
Scientists at A*STAR's Genome Institute of Singapore (GIS), in collaboration with their counterparts from Canada, Hong Kong and US, have discovered a protein mediator SON plays a critical role in the health and proper functioning ...
Cell & Microbiology
Sep 9, 2013
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