Unravelling the function of small RNAs

Small non-coding RNAs (ncRNAs) play a hitherto unrecognised role in regulation of gene expression. To broaden knowledge on the function and evolution of these molecules, a EU project investigated various classes of regulatory ...

The path from stem cell to maturity

Regulation of gene expression is essential to make sure cell maturation occurs as it should. European research is taking an integrated perspective on how selected steps in liver and blood cell differentiation can be modulated.

Transcriptional elongation control takes on new dimensions

Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in the process that ...

Conserved gene expression reveals our 'inner fish'

A study of gene expression in chickens, frogs, pufferfish, mice and people has revealed surprising similarities in several key tissues. Researchers writing in BioMed Central's open access Journal of Biology have shown that ...

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