Researchers led by Osaka University used cryogenic electron microscopy to analyze the atomic structure of the centromeric region of the chromosome, essential for cell division. A protein called CENP-A marks the centromere; ...
Cell & Microbiology
Feb 6, 2023
0
73
Watching a puppet show can teach you something about how estrogen works in the body, according to Rice University scientists whose research could open the door to new strategies for regulating the hormone—which could ...
Biochemistry
Jan 30, 2023
0
69
A recent study led by Assistant Professor of Gerontology Ryo Sanabria has identified a key protein that helps regulate the actin cytoskeleton, a scaffold of proteins within cells that makes their proper structure and function ...
Cell & Microbiology
Dec 12, 2022
0
5
Nucleotide excision repair (NER) is a critical DNA repair pathway that plays a key role in maintaining transcription and genome integrity by removing bulky DNA lesions.
Cell & Microbiology
Dec 8, 2022
0
71
For the first cell to develop into an entire organism, genes, RNA molecules and proteins have to work together in a complex way. At first, this process is indirectly controlled by the mother. At a certain point in time, the ...
Cell & Microbiology
Dec 6, 2022
0
108
New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...
Biochemistry
Dec 5, 2022
0
15
A defense mechanism that human cells possess against viruses such as monkeypox, herpes simplex and human papillomavirus—all double-stranded DNA viruses—relies on proteins that patrol the cell, acting as sensors of the ...
Biotechnology
Nov 29, 2022
0
39
The Plant Physiology and Biochemistry research team at the University of Konstanz has discovered previously unknown molecular mechanisms by which plants adapt to their environment—important basic knowledge in times of climate ...
Biochemistry
Nov 25, 2022
0
47
The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...
Biochemistry
Nov 3, 2022
0
32
Precise details of how a master regulator of gene expression binds its activating partner could open new avenues for cancer drug development.
Biochemistry
Oct 10, 2022
0
82
