Enzyme 'atlas' helps researchers decipher cellular pathways

One of the most important classes of human enzymes are protein kinases—signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction in these cellular pathways ...

Researchers discover a master regulator of plant immunity

The demonstration that a regulatory protein linked to stress responses in plants also serves as a master switch for anti-pathogen immunity could help breeders develop more pest-resistant and climate-resilient crops.

The first potent COQ8 inhibitor targets ubiquinone biosynthesis

A new collaborative study from the University of Eastern Finland, Washington University in St. Louis, University of Wisconsin–Madison, University of North Carolina at Chapel Hill and the Promega Corporation discloses the ...

Cancer drug could potentially be used against malaria

A cancer drug currently in clinical trials has shown the potential to protect from, cure, and prevent transmission of malaria. The breakthrough finding by an international team that includes researchers at Penn State offers ...

Elucidation of proteins controlling the sleep and awake transition

Professor Hiroki Ueda, Assistant Professor Daisuke Tone, Lecturer Koji Ode, and Qianhui Zhang (4th-year graduate student at the time) at the University of Tokyo showed that CaMKIIβ, a predominant protein kinase expressed ...

How a protein breaks free to cause deadly cancers

Better treatments for some of cancer's deadliest forms could be closer due to a University of California, Irvine-led discovery about how a certain protein is activated in tumor cells. The finding, spearheaded by researchers ...

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