Preventing resistance in cancer therapy

The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...

Efflux pump inhibitors: Bulking up to beat bacteria

The medical profession is in the midst of losing an arms race. Bacterial antibiotic resistance doesn't just threaten our ability to treat infection but our ability to carry out any treatment where infection is a risk. This ...

Cancer drug could potentially be used against malaria

A cancer drug currently in clinical trials has shown the potential to protect from, cure, and prevent transmission of malaria. The breakthrough finding by an international team that includes researchers at Penn State offers ...

Scientists map key protein structure of hepatitis C virus

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the hepatitis C virus (HCV) ...

Next-generation single-molecule protein sequencing technology

Researchers from Quantum-Si have published an article in Science that showcases how single-molecule protein sequencing via semiconductor chip and Time Domain Sequencing technologies will transform life science and biomedical ...

Researchers unlock a new method for testing protein-based drugs

New Jersey Institute of Technology (NJIT) researchers have unveiled a new lab technique they say represents a "paradigm shift" in how pharmaceutical laboratories test and produce new protein-based drugs, such as therapeutic ...

Analyzing the potential of AlphaFold in drug discovery

Over the past few decades, very few new antibiotics have been developed, largely because current methods for screening potential drugs are prohibitively expensive and time-consuming. One promising new strategy is to use computational ...

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