Many pharmaceuticals work by targeting what are known as 'G-protein-coupled receptors.' In a new study, scientists from Uppsala University describe how they have been able to predict how special molecules that can be used ...
Biochemistry
Jun 24, 2020
0
44
Rice University researchers have discovered a hidden symmetry in the chemical kinetic equations scientists have long used to model and study many of the chemical processes essential for life.
Biochemistry
Apr 30, 2020
0
2512
Researchers have developed a process that could sharply reduce the work involved in computational protein design, according to a study in Proceedings of the National Academy of Sciences.
Biochemistry
Feb 27, 2020
0
203
Proteins are the molecular machines that make all living things hum—they stop deadly infections, heal cells and capture energy from the sun. Yet because our basic understanding of how proteins work has until now remained ...
Molecular & Computational biology
Feb 7, 2020
4
55
Protein design is a popular and rapidly growing field, with scientists engineering novel protein cages—capsule-like nanostructures for purposes such as gene therapy and targeted drug delivery. Many of these structures fashioned ...
Biochemistry
Jan 23, 2020
0
210
EPFL scientists have developed a computational method modeling and designing protein allostery that allows the accurate and rational engineering and even repurposing of cell receptors. The method can be a significant tool ...
Biochemistry
Dec 2, 2019
0
36
Scientists have created the first completely artificial protein switch that can work inside living cells to modify—or even commandeer—the cell's complex internal circuitry.
Biochemistry
Jul 24, 2019
5
634
A single-molecule imaging technique, called protein-induced fluorescence enhancement (PIFE), has gained traction in recent years as a popular tool for observing DNA–protein interactions with nanometer precision. Yet, according ...
Biochemistry
Jul 24, 2019
0
35
The goal of the research, published July 11 in the journal Nature, was to engineer artificial proteins to self-assemble on a crystal surface by creating an exact match between the pattern of amino acids in the protein and ...
Biochemistry
Jul 10, 2019
0
218
A team of researchers encoded their specialized knowledge into the computer game Foldit to enable citizen scientists to successfully design synthetic proteins for the first time.
Biochemistry
Jun 5, 2019
0
765
