News tagged with prion disease
Scientists show 'lifeless' prions capable of evolutionary change and adaptation
Scientists from The Scripps Research Institute have determined for the first time that prions, bits of infectious protein devoid of DNA or RNA that can cause fatal neurodegenerative disease, are capable of Darwinian evolution.
Medicine & Health / Medical research
Dec 31, 2009 |
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Study points to disruption of copper regulation as key to prion diseases
(PhysOrg.com) -- An investigation of a rare, inherited form of Creutzfeldt-Jakob disease suggests that disrupted regulation of copper ions in the brain may be a key factor in this and other prion diseases.
Apr 17, 2009 |
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Research identifies drug target for prion diseases, 'mad cow'
Scientists at the University of Kentucky have discovered that plasminogen, a protein used by the body to break up blood clots, speeds up the progress of prion diseases such as mad cow disease.
Medicine & Health / Medical research
Jan 10, 2011 |
4.8 / 5 (5) |
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Scientists devise accelerated method to determine infectious prion strains
Current tests to identify specific strains of infectious prions, which cause a range of transmissible diseases (such as mad cow) in animals and humans, can take anywhere from six months to a year to yield results - a time-lag ...
Medicine & Health / Medical research
May 29, 2009 |
4.4 / 5 (5) |
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Dual role for immune cells in the brain
We all have at one time or another experienced the typical signs of an infection: the fever, the listlessness, the lack of appetite. They are orchestrated by the brain in response to circulating cytokines, ...
Medicine & Health / Neuroscience
Jan 13, 2010 |
4.4 / 5 (5) |
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Study shows infectious prions can arise spontaneously in normal brain tissue
In a startling new study that involved research on both sides of the Atlantic, scientists from The Scripps Research Institute in Florida and the University College London (UCL) Institute of Neurology in England have shown ...
Medicine & Health / Medical research
Jul 26, 2010 |
3.7 / 5 (6) |
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New sporadic prion protein disease identified
A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy (VPSPr), as it has been named, is the second type of complete sporadic disease to be identified since Creutzfeldt-Jakob disease ...
Medicine & Health / Neuroscience
Aug 13, 2010 |
4.8 / 5 (4) |
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Study Offers Evidence That Spongiform Brain Diseases Are Caused By Aberrant Protein
(PhysOrg.com) -- Scientists have determined how a normal protein can be converted into a prion, an infectious agent that causes fatal brain diseases in humans and mammals.
Medicine & Health / Medical research
Jan 28, 2010 |
4.3 / 5 (4) |
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Antibody key to treating variant CJD, scientists find
Scientists at the University of Liverpool have determined the atomic structure of the 'binding' between a brain protein and an antibody that could be key to treating patients with diseases such as variant CJD.
Medicine & Health / Diseases, Conditions, Syndromes
Mar 04, 2009 |
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Eyes of cattle may become new windows to detect mad cow disease
The eyes may or may not be windows to the soul, as the old adage goes, but scientists are reporting evidence that a peek into the eyes of cattle may become the basis for a long-sought test to detect infection ...
Chemistry / Analytical Chemistry
Jun 02, 2010 |
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BSE pathogens can be transmitted by air
Airborne prions are also infectious and can induce mad cow disease or Creutzfeldt-Jakob disorder. This is the surprising conclusion of researchers at the University of Zurich, the University Hospital Zurich and the University ...
Medicine & Health / Diseases, Conditions, Syndromes
Jan 13, 2011 |
5 / 5 (3) |
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Cellular stress can induce yeast to promote prion formation
It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, ...
Jul 23, 2011 |
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Size of protein aggregates, not abundance, drives spread of prion-based disease
Mad Cow disease and its human variant Creutzfeldt-Jakob disease, which are incurable and fatal, have been on a welcome hiatus from the news for years, but because mammals remain as vulnerable as ever to infectious diseases ...
Medicine & Health / Medical research
Oct 28, 2010 |
4.7 / 5 (3) |
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Prion leaves lasting mark on memory
Prions are a special class of proteins best known as the source for mad cow and other neurodegenerative diseases. Despite this negative reputation, according to a new report in the February 5th issue of the journal Cell a prio ...
Medicine & Health / Neuroscience
Feb 04, 2010 |
4.3 / 5 (3) |
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Researchers find new piece in Alzheimer's puzzle
Yale researchers have filled in a missing gap on the molecular road map of Alzheimer's disease. In the Feb. 26 issue of the journal Nature, the Yale team reports that cellular prion proteins trigger the process by which ...
Medicine & Health / Diseases, Conditions, Syndromes
Feb 25, 2009 |
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