People with chronic pain are often dependent on drugs from the class of opioids with sometimes considerable side effects. Accordingly, in recent years the search for safer alternatives has been the focus of new drug discovery.
Biochemistry
Dec 6, 2023
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20
Capsaicin, the active ingredient in chili peppers, is most often experienced as an irritant, but it may also be used to reduce pain. A new work published by Drs. Feng Qin and Jing Yao in this week's PLoS Biology uses capsaicin ...
Feb 24, 2009
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0
Researchers have long sought alternatives to morphine – a powerful and widely used painkiller – that curb its side effects, including dependency, nausea and dizziness. Now, an experiment at the Department of Energy's ...
Biotechnology
Feb 18, 2015
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50
Chemical biologists at LMU have synthesized a set of molecules which make it possible to optically control the function of nerve cells that mediate perception of painful stimuli.
Biochemistry
Jun 3, 2015
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12
In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring ...
Molecular & Computational biology
Jan 12, 2023
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24
Lynne Sneddon is a myth buster. Having debunked the fisherman's legend that fish don't feel pain, Sneddon, from the University of Liverpool, UK, has become a leading figure in the movement to reduce, replace and refine the ...
Plants & Animals
Apr 19, 2017
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6
