News tagged with nuclear pore

Nuclear pore complexes harbor new class of gene regulators

Nuclear pore complexes are best known as the communication channels that regulate the passage of all molecules to and from a cell's nucleus. Researchers at the Salk Institute for Biological Studies, however, ...

Biology / Cell & Microbiology

created Feb 04, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Biologists reveal structure of cell nucleus 'gatekeeper'

(PhysOrg.com) -- Biologists led by associate professor Thomas Schwartz (MIT) have worked out a rudimentary architectural plan for the nuclear pore complex (NPC), the gatekeeper of the cell's nucleus.

Biology / Cell & Microbiology

created Oct 27, 2009 | popularity 4.2 / 5 (6) | comments 6

Come on in: Nuclear barrier less restrictive than expected in new cells

When it comes to the two basic types of cells, prokaryotes and eukaryotes, compartmentalization is everything. Prokaryotes are evolutionarily ancient cells that only have a membrane surrounding their outer boundary, while ...

Chemistry / Biochemistry

created Oct 06, 2009 | popularity not rated yet | comments 0

'Promiscuous' protein interactions found in the nuclear pore complex

(PhysOrg.com) -- The NPC is the only way in or out of a cell's nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further ...

Biology / Cell & Microbiology

created Sep 29, 2009 | popularity 5 / 5 (1) | comments 0

Solving the Nuclear Pore Puzzle

(PhysOrg.com) -- Computational biochemist Frank Alber compares determining the architecture of a macromolecular machine to solving a jigsaw puzzle.

Chemistry / Biochemistry

created Aug 19, 2009 | popularity not rated yet | comments 0

New research supports model for nuclear pore complex

(PhysOrg.com) -- To protect their DNA, cells in higher organisms are very choosy about what they allow in and out of their nuclei, where the genes reside. Guarding access is the job of transport machines called nuclear pore ...

Biology / Cell & Microbiology

created Aug 18, 2009 | popularity not rated yet | comments 0

Research suggests core nuclear pore elements shared by all eukaryotes

(PhysOrg.com) -- For perhaps 1.8 billion years after life first emerged on Earth, a sort of evolutionary writer’s block stalled the development of organisms more complicated than single cells. Then, a burst of experimental ...

Chemistry / Biochemistry

created Jul 13, 2009 | popularity 5 / 5 (1) | comments 0

Research identifies 3-D structure of key nuclear pore building block

The genome of complex organisms is stashed away inside each cell's nucleus, a little like a sovereign shielded from the threatening world outside. The genome cannot govern from its protective chamber, however, without knowing ...

Biology / Cell & Microbiology

created Jun 07, 2009 | popularity 5 / 5 (1) | comments 0

The breakdown of barriers in old cells may hold clues to aging process

Like guards controlling access to a gated community, nuclear pore complexes are communication channels that regulate the passage of proteins and RNA to and from a cell's nucleus. Recent studies by researchers ...

Biology /

created Jan 22, 2009 | popularity 5 / 5 (4) | comments 0

Researchers construct a device that mimics one of nature's key transport machines

(PhysOrg.com) -- To help protect its genes, a cell is highly selective about what it allows to move in and out of its nucleus. Yet that choosiness is regulated by just a thin barrier, perforated with tiny ...

Biology /

created Jan 06, 2009 | popularity 4.7 / 5 (7) | comments 0

Structural study backs new model for the nuclear pore complex

(PhysOrg.com) -- In higher organisms, the genetic material is confined and protected in the cell nucleus. In order for a healthy cell to function, the DNA must send manufacturing orders through the double ...

Biology /

created Dec 24, 2008 | popularity 4.7 / 5 (3) | comments 0


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