Related topics: cells

The point of no return: Chromatin enforces cell fate decisions

Stem cells balance self-renewal with differentiation into mature cells. A fundamental and intriguing question is when during the process of maturation a cell reaches a "point of no return," losing its capacity to self-renew ...

New insights into the epigenetic control of hematopoiesis

Scientists at The Wistar Institute have characterized a novel function for the INTS13 protein that is part of a large protein complex regulating gene transcription, called Integrator. According to study results, published ...

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