News tagged with mutant cells

M6P deficiency leaves B cells out of sorts

A group of white blood cells known as B cells, which play a key role in the human immune response, need a protein-targeting signal called mannose 6-phosphate (M6P) in order to proliferate, differentiate, and present immune ...

dateJan 19, 2015 in Cell & Microbiology
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Negative feedback makes cells 'sensitive'

New research has shown that negative feedback loops in cell signalling systems can be essential for a cell's ability to perceive the strength of a growth stimulus. Cells lacking the feedback loop became insensitive to the ...

dateJan 08, 2014 in Cell & Microbiology
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Mitochondrial cooperatives

Mitochondria, the organelles that supply the cell with energy, are highly dynamic and can link up to form complex tubular networks. A new study shows that this response can transiently compensate for a shortfall in energy ...

dateAug 13, 2013 in Cell & Microbiology
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