New type of triterpenes discovered

A collaborative effort has revealed a new type of triterpene, a group of organic compounds which are an important source of many medicines. Until now, all triterpenes were believed to be derived from squalene, itself a type ...

Self-regulation of an enzyme with critical cellular functions

The lab of Kathy Gould, Louise B. McGavock Professor and professor of cell and developmental biology, used a multi-disciplinary approach that included structural biology, biochemistry, and molecular biology to investigate ...

Using 'counterfactuals' to verify predictions of drug safety

Scientists rely increasingly on models trained with machine learning to provide solutions to complex problems. But how do we know the solutions are trustworthy when the complex algorithms the models use are not easily interrogated ...

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