Changes in cellular degradation hubs can lead to cancer

Cancer cells grow and divide in an uncontrolled manner. A new study from Uppsala University now shows how alterations in a cell's degradation hubs, called lysosomes, can cause abnormal cell growth. The results are published ...

Why cells need acidic lysosomes

Just like the body contains lungs, liver, and lymph nodes, so does each of the body's cells contain tiny specialized organs. Perhaps most peculiar among them are lysosomes—bubble-like sacks that act as part recycling bin, ...

Biological risk potential of nanoparticles studied

Carbon nanoparticles are a promising tool for biomedical applications, for example, for targeted transportation of biologically active compounds into cells. A team of researchers from the Physics, Medicine and Chemistry departments ...

Long live Nemo! New animal model in aging research?

The colorful Clownfish lives longer than 20 years in the aquarium. Researchers of the Scuola Normale Superiore in Pisa, Italy, in collaboration with the Leibniz Institute on Aging (FLI) in Jena, Germany, have investigated ...

Cellular recycling caught in the act

A team of researchers at the Center for Self-assembly and Complexity, within the Institute for Basic Science (IBS) have observed a normal physiological process, called "self-eating", that cells use to recycle their components. ...

Lyosomes and mitochondria chat each other up in cell

Northwestern Medicine scientists have discovered that two key cellular structures, called mitochondria and lysosomes, come into direct contact with each other in the cell to regulate their respective functions. This rare ...

Scientists report inhibition of cellular aging

Aging is the deterioration of a cell's ability to divide and grow as it gets older. This causes degradation of the body and age-related diseases. Prevention of aging is an instinctive desire of humans; thus, it is a task ...

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