A new mechanism for accessing damaged DNA

UV light damages the DNA of skin cells, which can lead to skin cancer. But this process is counteracted by DNA repair machinery, acting as a molecular sunscreen. It has been unclear, however, how repair proteins work on DNA ...

Frog eggs help researchers understand repair of DNA damages

The DNA replication process in which cells divide to create new cells also triggers repair of DNA damage, researchers from the University of Copenhagen report in a new study. The researchers studied extracts from frog eggs, ...

Study reveals how enzyme detects ultraviolet light damage

Damage to DNA is a constant threat to cellular life, and so it is constantly monitored and detected by a family of enzymes called RNA polymerases, resulting in subsequent repair to maintain genome integrity. In a paper published ...

Deciphering potent DNA toxin's secrets

One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.

Stressed out: Scientist details cells' response to lesions

In a recent review paper published in Nature Structural & Molecular Biology, SLU scientist Alessandro Vindigni, Ph.D., describes the strategies cells use when their DNA faces replication stress, challenges that may derail ...

Suspicious pigment spots more common on darker skin

(HealthDay)—People with darker skin are about one-third more likely to have potentially dangerous pigment "spots" on their palms and soles, a new study finds.

Gel filled with nanosponges cleans up MRSA infections

Nanoengineers at the University of California, San Diego developed a gel filled with toxin-absorbing nanosponges that could lead to an effective treatment for skin and wound infections caused by MRSA (methicillin-resistant ...

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