A better HIV test

Public health officials have a tough choice to make when it comes to screening people for HIV: administer a reliable blood test that can detect infections early on, but that few people will volunteer for, or give people a ...

Mathematically modeling HIV drug pharmacodynamics

37 million people around the world today live with Human Immunodeficiency Virus (HIV), which is responsible for roughly 1.1 million deaths caused by AIDS-related conditions.

Storming the cellular barricades to fight fungi

Yale scientists have developed a new class of small molecules that attack fungal infections by clinging to the cell wall of harmful fungi and recruiting a swarm of antibodies to join the fight.

Restricting HIV-1 infection

The HIV-1 capsid protein (CA) interacts with viral factors that support infection and host factors that restrict it. The host protein cyclophilin A (CypA) binds to CA and enhances the action of host restriction factors that ...

HIV hijacks surface molecule to invade cell

Researchers at the National Institutes of Health have discovered a key step in the process that HIV uses to inject its genetic material into cells. Working with cultures of cells and tissues, the researchers prevented the ...

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