Early migrations of humans to the Americas from Siberia around 12,000 years ago have been traced using the bacteria they carried by an international team including scientists at the University of Warwick.
Evolution
Jun 14, 2021
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410
Engineers at the University of California San Diego have developed a miniature device that's sensitive enough to feel the forces generated by swimming bacteria and hear the beating of heart muscle cells.
Optics & Photonics
May 15, 2017
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1367
In a scientific breakthrough, Monash University researchers have discovered a revolutionary "U-turn" in the evolution of antibiotic resistance, challenging the widely accepted notion that traits once developed are irreversible.
Evolution
Jan 5, 2024
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119
LMU researchers have discovered a weakness in the bacterium Helicobacter pylori, which could be exploited to develop new drugs.
Cell & Microbiology
Apr 26, 2023
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More than half of the world's population carries the bacterium Helicobacter pylori in their stomach mucosa. It often causes no problems throughout life, but sometimes it can cause inflammation, and in some cases, it can even ...
Cell & Microbiology
Oct 15, 2020
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82
Stomach cancer is the third-leading cause of cancer-related death across the globe. One of the main risk factors for this disease is infection with the bacterium Helicobacter pylori. About half of the world's population is ...
Cell & Microbiology
Jan 23, 2020
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Scientists have uncovered a novel antibiotic-free approach that could help prevent and treat one of the most widespread bacterial pathogens, using nanocapsules made of natural ingredients.
Bio & Medicine
Oct 17, 2019
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95
Scientists from the Institut Pasteur and CNRS have recently identified new strategies used by Helicobacter pylori bacteria to infect cells. By specifically targeting mitochondria, these bacteria, despite being extracellular, ...
Cell & Microbiology
Nov 29, 2017
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21
A new shape-shifting polymer can target and kill Helicobacter pylori bacteria in the stomach without killing helpful bacteria in the gut. Such a treatment could improve the digestive health of billions of people worldwide ...
Biochemistry
Nov 14, 2017
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21
Half of all people are chronically infected with Helicobacter pylori, a Gram negative bacterium that plays a causative role in the development of gastric cancer. It comes in two types, one that is relatively harmless and ...
Cell & Microbiology
Sep 6, 2017
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Helicobacter pylori (pronounced /ˌhɛlɪkɵˈbæktər pɪˈlɔəraɪ/) is a Gram-negative, microaerophilic bacterium that inhabits various areas of the stomach and duodenum. It causes a chronic low-level inflammation of the stomach lining and is strongly linked to the development of duodenal and gastric ulcers and stomach cancer. Over 80% of individuals infected with the bacterium are asymptomatic.
The bacterium was initially named Campylobacter pyloridis, then renamed C. pylori to correct a Latin grammar error. When 16S rRNA gene sequencing and other research showed in 1989 that the bacterium did not belong in the genus Campylobacter, it was placed in its own genus, Helicobacter. The genus derived from the Ancient Greek hělix/έλιξ "spiral" or "coil". The specific epithet pylōri means "of the pylorus" or pyloric valve (the circular opening leading from the stomach into the duodenum), from the Ancient Greek word πυλωρός, which means gatekeeper.
More than 50% of the world's population harbour H. pylori in their upper gastrointestinal tract. Infection is more prevalent in developing countries, although incidence is decreasing in western countries. The route of transmission is unknown, although individuals become infected in childhood. H. pylori's helix shape (from which the generic name is derived) is thought to have evolved to penetrate the mucoid lining of the stomach.
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