Researchers at Montana State University have found a method for creating more robust, temperature-tolerant enzymes that can be used as tools in the process of genetic manipulation.
Biotechnology
Sep 7, 2012
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(Phys.org)—Scientists on the Florida campus of The Scripps Research Institute have designed a compound that shows promise as a potential therapy for one of the diseases closely linked to fragile X syndrome, a genetic condition ...
Biochemistry
Sep 4, 2012
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(Phys.org) -- In a new study, UT Dallas researchers outline how they used fluorescent molecules to "tag" DNA and monitor a process called DNA looping, a natural biological mechanism involved in rearranging genetic material ...
Cell & Microbiology
Aug 13, 2012
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There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process. The rule-flaunting ...
Biotechnology
May 17, 2012
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Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing - a critical step in the earliest stage of protein production. Their study appears in the ...
Cell & Microbiology
Sep 23, 2010
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Researchers in human genetics have long known that expansions of GAA repeats - resulting in this nucleotide triplet repeating hundreds or thousands of times - cause the most common hereditary neurological disorder known as ...
Cell & Microbiology
Jul 9, 2009
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The widely-used Affymetrix Whole-Transcript Gene 1.0 ST (sense target) microarray platform, normally used to assay gene expression, can also be utilized to interrogate exon-specific splicing. Research published today in the ...
Other
May 21, 2009
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(PhysOrg.com) -- Isaac Edery is concerned with biological clocks, internal mechanisms that enable virtually all plants and animals to behave in rhythmic biological cycles known as circadian rhythms.
Jan 28, 2009
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Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia ...
Jan 28, 2009
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