News tagged with drug target

Related topics: new drugs , cancer cells , protein

Hitting moving RNA drug targets

By accounting for the floppy, fickle nature of RNA, researchers at the University of Michigan and the University of California, Irvine have developed a new way to search for drugs that target this important molecule. Their ...

Chemistry / Biochemistry

created Jun 26, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Boosting research into new drugs: 'Smart materials' make proteins form crystals

Scientists have developed a new method to make proteins form crystals using 'smart materials' that remember the shape and characteristics of the molecule. The technique, reported today in Proceedings of the National Academy of ...

Chemistry / Materials Science

created Jun 20, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Team develops new weapon to fight disease-causing bacteria, malaria

Researchers report that they have discovered - and now know how to exploit - an unusual chemical reaction mechanism that allows malaria parasites and many disease-causing bacteria to survive. The research ...

Chemistry / Biochemistry

created Feb 15, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

A single atom controls motility required for bacterial infection

Bacteria can swim, propelling themselves through fluids using a whip-like extension called a flaggella. They can also walk, strolling along solid surfaces using little fibrous legs called pili. It is this ...

Biology / Cell & Microbiology

created Jan 04, 2010 | popularity 4.9 / 5 (10) | comments 0 | with audio podcast

New findings reveal how influenza virus hijacks human cells

Influenza is and remains a disease to reckon with. Seasonal epidemics around the world kill several hundred thousand people every year. In the light of looming pandemics if bird flu strains develop the ability ...

Biology /

created Feb 04, 2009 | popularity 4.6 / 5 (5) | comments 0

3D structure opens new avenue for drug discovery

(PhysOrg.com) -- An international consortium has determined the structure of an important new drug target in complex with a synthetic molecule designed by our researchers, opening up new avenues for drug discovery.

Chemistry / Biochemistry

created Apr 02, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists create potent molecules aimed at treating muscular dystrophy

While RNA is an appealing drug target, small molecules that can actually affect its function have rarely been found. But now scientists from the Florida campus of The Scripps Research Institute have for the first time designed ...

Chemistry / Biochemistry

created Feb 22, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Genetic code cracked for a devastating blood parasite

(PhysOrg.com) -- Scientists have cracked the genetic code and predicted some high priority drug targets for the blood parasite Schistosoma haematobium, which is linked to bladder cancer and HIV/ AIDS and causes the insidious ...

Biology / Biotechnology

created Jan 18, 2012 | popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Scientists characterize protein essential to survival of malaria parasite

A biology lab at Washington University has just cracked the structure and function of a protein that plays a key role in the life of a parasite that killed 655,000 people in 2010.

Chemistry / Biochemistry

created Jan 06, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

How fruit flies can teach us about curing chronic pain and halting mosquito-borne diseases

Studies of a protein that fruit flies use to sense heat and chemicals may someday provide solutions to human pain and the control of disease-spreading mosquitoes.

Biology / Cell & Microbiology

created Dec 06, 2011 | popularity not rated yet | comments 0 | with audio podcast

Scientists uncover new role for gene in maintaining steady weight

Against the backdrop of the growing epidemic of obesity in the United States, scientists from the Florida campus of The Scripps Research Institute have made an important new discovery regarding a specific gene that plays ...

Chemistry / Biochemistry

created Nov 23, 2011 | popularity 4.2 / 5 (6) | comments 2 | with audio podcast

Cancer drug cisplatin found to bind like glue in cellular RNA

An anti-cancer drug used extensively in chemotherapy binds pervasively to RNA -- up to 20-fold more than it does to DNA, a surprise finding that suggests new targeting approaches might be useful, according to University of ...

Chemistry / Biochemistry

created Nov 21, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Nanoparticles working in harmony

For decades, researchers have been working to develop nanoparticles that deliver cancer drugs directly to tumors, minimizing the toxic side effects of chemotherapy. However, even with the best of these nanoparticles, only ...

Nanotechnology / Bio & Medicine

created Jul 15, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Researchers design a better way to discover drug candidates

(PhysOrg.com) -- Yale researchers have devised a novel way to trick cells into getting rid of problematic proteins, a method that could help pharmaceutical companies quickly identify promising targets for new drugs.

Chemistry / Biochemistry

created Jul 04, 2011 | popularity 4 / 5 (2) | comments 0 | with audio podcast

New drugs target delay of Huntington's symptoms

(Medical Xpress) -- McMaster researchers have discovered a new drug target that may be effective at preventing the onset of Huntington's disease, working much the same way heart medications slow the progression of heart disease ...

Chemistry / Biochemistry

created May 31, 2011 | popularity 4 / 5 (1) | comments 0 | with audio podcast