Microorganisms possess natural product biosynthetic gene clusters (BGCs) that may harbor unique bioactivities for use in drug development and agricultural applications. However, many uncharacterized microbial BGCs remain ...
Molecular & Computational biology
Feb 19, 2021
0
84
New high-resolution structures of the bacterial ribosome determined by researchers at the University of Illinois Chicago show that a single water molecule may be the cause—and possible solution—of antibiotic resistance.
Biochemistry
Jan 19, 2021
0
230
Scientists studying the body's natural defenses against bacterial infection have identified a nutrient—taurine—that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn). ...
Cell & Microbiology
Jan 15, 2021
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1533
A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in experimentally evolving the common bacteria Escherichia coli under pressure from a large number of individual antibiotics. ...
Cell & Microbiology
Nov 24, 2020
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121
There is no hole-in-one drug treatment when it comes to the flu, but that doesn't stop scientists from trying to sink one. Especially since as many as one in five Americans gets the flu. The reported estimated cost of this ...
Cell & Microbiology
Nov 20, 2020
0
9
For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a ...
Evolution
Nov 18, 2020
0
45
Many patients with pancreatic cancer have only about a 10% chance of survival within five years of their diagnosis because they tend to become resistant to chemotherapy, past studies have indicated.
Analytical Chemistry
Oct 29, 2020
0
123
National University of Singapore researchers have developed an approach to selectively target pathogenic bacteria by harnessing an intracellular metabolite known as formate, abundant in these bacteria, as a new antimicrobial ...
Biochemistry
Oct 9, 2020
0
16
Published in Nature Physics, findings from a new study co-led by Cleveland Clinic and Case Western Reserve University teams show for the first time how ideas from quantum physics can help develop novel drug interventions ...
General Physics
Aug 24, 2020
0
446
Bacteria—tiny and in some cases deadly single-celled organisms—are far more complex than commonly thought.
Cell & Microbiology
Jul 30, 2020
0
222
