A collaborative effort has revealed a new type of triterpene, a group of organic compounds which are an important source of many medicines. Until now, all triterpenes were believed to be derived from squalene, itself a type ...
Biochemistry
Jun 1, 2022
0
140
(Phys.org)—Drug design involves guided trial-and-error. How the body metabolizes a particular drug is important for determining drug efficacy. There have been many studies to understand how xenobiotics interact with cytochrome ...
A team of Yale University scientists has synthesized for the first time a chemical compound called lomaiviticin aglycon, leading to the development of a new class of molecules that appear to target and destroy cancer stem ...
Biochemistry
Jan 31, 2011
0
0
A new automated workflow developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) has the potential to allow researchers to analyze the products of their reaction experiments in real time, a key capability ...
Analytical Chemistry
Apr 8, 2024
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42
Using electricity, a new method offers the possibility of recycling CO2 while also performing a notoriously difficult reaction, producing compounds potentially useful for drug development.
Analytical Chemistry
Feb 22, 2022
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88
Vanderbilt biochemists have discovered that the process bacteria undergo when they become drug resistant can act as a powerful tool for drug discovery.
Biochemistry
Jan 25, 2013
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0
Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in human blood, but they don't prevent infection or transmission via mosquitoes. What's ...
Cell & Microbiology
Dec 6, 2018
0
64
A newly developed compound starves cancer cells by attacking their "power plants"—the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max ...
Molecular & Computational biology
Dec 22, 2020
2
16
Anti-diabetic drugs may become cheaper and more accessible thanks to a breakthrough from CSIRO, Australia's national science agency.
Bio & Medicine
Oct 1, 2019
0
17
Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings, which were reported in the ...
Molecular & Computational biology
Sep 7, 2023
0
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