In the first experimental use of algorithms that employ structure-based molecular modeling to optimize deimmunized drug candidates, Karl Griswold, PhD, and co-investigator Christopher Bailey-Kellogg, PhD of Dartmouth College ...
Biotechnology
Feb 13, 2015
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431
Chemists at The Scripps Research Institute (TSRI) have devised a greatly improved technique for making amino acids not found in nature. These "unnatural" amino acids traditionally have been very difficult to synthesize, but ...
Biochemistry
Mar 13, 2014
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0
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have described a pair of drug candidates that advance the search for new treatments for pain, addiction and other disorders.
Biochemistry
Jan 13, 2014
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(Phys.org) —James Bond had his reasons for ordering his martinis "shaken, not stirred." Similarly, drug manufacturers need to make sure the molecules in a new drug are arranged in an exact manner, lest there be dire consequences. ...
Materials Science
Aug 15, 2013
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0
(Phys.org) —Employers are increasingly using Facebook to screen job applicants and weed out candidates they think have undesirable traits. But a new study from North Carolina State University shows that those companies ...
Economics & Business
Jul 2, 2013
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The Ebola virus is among the deadliest viruses on the planet, killing up to 90% of those infected, and there are no approved vaccines or effective therapies. A study published by Cell Press on May 7th in the Biophysical Journal ...
Cell & Microbiology
May 7, 2013
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0
(Phys.org) -- A cross-disciplinary team of researchers at the University of Maryland has designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly 3000 times. Their ...
Biochemistry
May 7, 2012
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0
(PhysOrg.com) -- Some drugs may be more effective the longer they last inside the body. To prevent such drugs from being broken down too rapidly, pharmaceutical manufacturers often attach a fluorine-containing structure called ...
Biochemistry
Jun 24, 2010
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0
(PhysOrg.com) -- In the last 10 years, the growth of the Internet has made ranking algorithms one of the hottest topics in computer science. The most famous ranking algorithm is Google's, which determines the order of search ...
Other
Apr 14, 2010
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0
(PhysOrg.com) -- A robust new technique for screening drugs' effects on zebrafish behavior is pointing Harvard University scientists toward unexpected compounds and pathways that may govern sleep and wakefulness in humans.
Cell & Microbiology
Jan 14, 2010
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