News tagged with disease mechanisms
Speeding up drug discovery with rapid 3-D mapping of proteins
A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets ...
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Researchers create first custom designed protein crystal
Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. University of Pennsylvania chemists have taken this kind of design ...
Apr 25, 2012 |
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To drive infections, a hijacking virus mimics a cell's signaling system
New biological research reveals how an invading virus hijacks a cell's workings by imitating a signaling marker to defeat the body's defenses. By manipulating cell signals, the virus destroys a defensive protein designed ...
Mar 26, 2012 |
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Scientists develop novel technique to map protein interactions leading to better understanding of disease mechanisms
Scientists have developed a powerful new technique, named BioID, to screen for both interacting and neighboring proteins in their native cellular environment. Elucidating protein interactions is key to better understanding ...
Mar 15, 2012 |
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Toxins from diseased brain cells make diseases of the brain even worse
Sometimes our immune defence attacks our own cells. When this happens in the brain we see neurodegenerative diseases such as dementia, Alzheimer's and Parkinson's disease. But if the the immune defence is inhibited, the results ...
Feb 22, 2012 |
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Shedding light on how body fends off bacteria
To invade organisms such as humans, bacteria make use of a protein called flagellin, part of a tail-like appendage that helps the bacteria move about. Now, for the first time, a team led by scientists at The ...
Feb 16, 2012 |
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Prion proteins play powerful role in survival, evolution of wild yeast strains
Prions, the much-maligned proteins most commonly known for causing "mad cow" disease, are commonly used in yeast to produce beneficial traits in the wild. Moreover, such traits can be passed on to subsequent generations and ...
Feb 15, 2012 |
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Roundworm research reviewed in Science publication
There are 16,000 types of parasitic roundworms causing illnesses in humans and animals. Controlling their effects on health becomes more difficult as the medicines used to treat them become less effective. A University of ...
Feb 03, 2012 |
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Method identifies mutations that drive genetic diseases
(PhysOrg.com) -- For the first time, a new computational method allows researchers to identify which specific molecular mechanisms are altered by genetic mutations in proteins that lead to disease. And they ...
Jan 19, 2012 |
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'First step' to perfect drug combinations
The researchers found a way of identifying ideal drug combinations from billions of others which would prevent inflammation from occurring.
Oct 23, 2011 |
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How Wolbachia bacteria controls vectors of deadly diseases
Researchers at Boston University have made discoveries that provide the foundation towards novel approaches to control insects that transmit deadly diseases such as dengue fever and malaria through their study of the Wolbachia bacter ...
Oct 20, 2011 |
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Examining rice genes for rice blast resistance
U.S. Department of Agriculture (USDA) scientists have characterized the molecular mechanism behind some plants' ability to resist rice blast, a fungal disease that affects cereal grain crops such as rice, wheat, rye and barley ...
Oct 17, 2011 |
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Curry spice could offer treatment hope for tendinitis
(PhysOrg.com) -- A derivative of a common culinary spice found in Indian curries could offer a new treatment hope for sufferers of the painful condition tendinitis, an international team of researchers has shown.
Aug 09, 2011 |
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A possible new target for treatment of multiple sclerosis
The immune system recognizes and neutralizes or destroys toxins and foreign pathogens that have gained access to the body. Autoimmune diseases result when the system attacks the body's own tissues instead. One of the most ...
Medicine & Health / Medical research
Mar 27, 2011 |
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Molecule that spurs cell's recycling center may help Alzheimer's patients
Cells, which employ a process called autophagy to clean up and reuse protein debris leftover from biological processes, were the original recyclers. A team of scientists from Paul Greengard's Rockefeller University laboratory ...
Medicine & Health / Medical research
Mar 16, 2011 |
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