News tagged with disease mechanisms

Speeding up drug discovery with rapid 3-D mapping of proteins

A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets ...

Chemistry / Biochemistry

created 8 hours ago | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers create first custom designed protein crystal

Protein design is technique that is increasingly valuable to a variety of fields, from biochemistry to therapeutics to materials engineering. University of Pennsylvania chemists have taken this kind of design ...

Chemistry / Materials Science

created Apr 25, 2012 | popularity 5 / 5 (3) | comments 1 | with audio podcast

To drive infections, a hijacking virus mimics a cell's signaling system

New biological research reveals how an invading virus hijacks a cell's workings by imitating a signaling marker to defeat the body's defenses. By manipulating cell signals, the virus destroys a defensive protein designed ...

Biology / Cell & Microbiology

created Mar 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists develop novel technique to map protein interactions leading to better understanding of disease mechanisms

Scientists have developed a powerful new technique, named BioID, to screen for both interacting and neighboring proteins in their native cellular environment. Elucidating protein interactions is key to better understanding ...

Biology / Cell & Microbiology

created Mar 15, 2012 | popularity 3 / 5 (1) | comments 0

Toxins from diseased brain cells make diseases of the brain even worse

Sometimes our immune defence attacks our own cells. When this happens in the brain we see neurodegenerative diseases such as dementia, Alzheimer's and Parkinson's disease. But if the the immune defence is inhibited, the results ...

Chemistry / Biochemistry

created Feb 22, 2012 | popularity 5 / 5 (1) | comments 0

Shedding light on how body fends off bacteria

To invade organisms such as humans, bacteria make use of a protein called flagellin, part of a tail-like appendage that helps the bacteria move about. Now, for the first time, a team led by scientists at The ...

Biology / Cell & Microbiology

created Feb 16, 2012 | popularity 4 / 5 (2) | comments 0 | with audio podcast

Prion proteins play powerful role in survival, evolution of wild yeast strains

Prions, the much-maligned proteins most commonly known for causing "mad cow" disease, are commonly used in yeast to produce beneficial traits in the wild. Moreover, such traits can be passed on to subsequent generations and ...

Biology / Cell & Microbiology

created Feb 15, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Roundworm research reviewed in Science publication

There are 16,000 types of parasitic roundworms causing illnesses in humans and animals. Controlling their effects on health becomes more difficult as the medicines used to treat them become less effective. A University of ...

Biology / Cell & Microbiology

created Feb 03, 2012 | popularity not rated yet | comments 0

Method identifies mutations that drive genetic diseases

(PhysOrg.com) -- For the first time, a new computational method allows researchers to identify which specific molecular mechanisms are altered by genetic mutations in proteins that lead to disease. And they ...

Biology / Biotechnology

created Jan 19, 2012 | popularity 4 / 5 (2) | comments 0 | with audio podcast

'First step' to perfect drug combinations

The researchers found a way of identifying ideal drug combinations from billions of others which would prevent inflammation from occurring.

Chemistry / Biochemistry

created Oct 23, 2011 | popularity 5 / 5 (3) | comments 2 | with audio podcast

How Wolbachia bacteria controls vectors of deadly diseases

Researchers at Boston University have made discoveries that provide the foundation towards novel approaches to control insects that transmit deadly diseases such as dengue fever and malaria through their study of the Wolbachia bacter ...

Biology / Cell & Microbiology

created Oct 20, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Examining rice genes for rice blast resistance

U.S. Department of Agriculture (USDA) scientists have characterized the molecular mechanism behind some plants' ability to resist rice blast, a fungal disease that affects cereal grain crops such as rice, wheat, rye and barley ...

Biology / Biotechnology

created Oct 17, 2011 | popularity not rated yet | comments 0

Curry spice could offer treatment hope for tendinitis

(PhysOrg.com) -- A derivative of a common culinary spice found in Indian curries could offer a new treatment hope for sufferers of the painful condition tendinitis, an international team of researchers has shown.

Chemistry / Biochemistry

created Aug 09, 2011 | popularity 4 / 5 (1) | comments 0

A possible new target for treatment of multiple sclerosis

The immune system recognizes and neutralizes or destroys toxins and foreign pathogens that have gained access to the body. Autoimmune diseases result when the system attacks the body's own tissues instead. One of the most ...

Medicine & Health / Medical research

created Mar 27, 2011 | popularity 5 / 5 (2) | comments 2 | with audio podcast

Molecule that spurs cell's recycling center may help Alzheimer's patients

Cells, which employ a process called autophagy to clean up and reuse protein debris leftover from biological processes, were the original recyclers. A team of scientists from Paul Greengard's Rockefeller University laboratory ...

Medicine & Health / Medical research

created Mar 16, 2011 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast