Cryo-EM reveals how '911' molecule helps fix damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.

DNA replication under the microscope

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

How cells defend against influenza A virus

Human cells use a protein named TBC1D5 to route influenza A viruses inside host cells for destruction, preventing the virus from spreading replicated copies of itself to other cells, according to a study published in Nature ...

Understanding the origin of genetic instability

Researchers at the Andalusian Molecular Biology and Regenerative Medicine Centre (CABIMER) and the University of Seville have taken another step in the study of genetic instability, as manifested in cancer cells. This has ...

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