A Penn team describes how a key cell-movement protein called IRSp53 is regulated in a resting and active state, and what this means for cancer-cell metastasis. They characterized how IRSp53 connects to the cell-motility machinery ...
Cell & Microbiology
Mar 12, 2014
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Researchers at the Buck Institute have identified and categorized thousands of protein interactions involving huntingtin, the protein responsible for Huntington's disease (HD). To use an analogy of a human social network, ...
Biochemistry
Feb 27, 2014
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(Phys.org) —The primary cilium plays the role of conductor, and antenna, to many kinds of cells. In photoreceptors, the cilium has been morphed into an expansive pigment-infused photon sieve, while in olfactory cells it ...
University of Oregon biochemists have determined how tiny synthetic molecules disrupt an important actin-related molecular machine in cells in one study and, in a second one, the crystal structure of that machine when bound ...
Cell & Microbiology
Jul 29, 2013
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(Phys.org)—The amoeba Acanthamoeba cunningly traps motile bacteria, collecting them in a rucksack before devouring the whole backpack. This behaviour of the single-cell organisms is unique.
Cell & Microbiology
Oct 22, 2012
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Cells on the move reach forward with lamellipodia and filopodia, cytoplasmic sheets and rods supported by branched networks or tight bundles of actin filaments. Cells without functional lamellipodia are still highly motile ...
Cell & Microbiology
Apr 9, 2012
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(PhysOrg.com) -- Cornell researchers have peered into the complex molecular network of receptors that give one-celled organisms like bacteria the ability to sense their environment and respond to chemical changes as small ...
Cell & Microbiology
Feb 20, 2012
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(PhysOrg.com) -- For better and for worse, human health depends on a cell's motility -- the ability to crawl from place to place. In every human body, millions of cells –are crawling around doing mostly good deeds -- ...
Cell & Microbiology
Oct 18, 2011
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Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that members of an enzyme family found in humans and throughout the plant and animal kingdoms play a crucial role in regulating cell ...
Cell & Microbiology
Mar 18, 2011
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Centrioles are barrel-shaped connection hubs that, like key Meccano parts, hold together the microtubule connection rods that form the structural framework of the cells in our bodies.
Biochemistry
Feb 1, 2011
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