Crinkled coatings could prevent medical implants from failing

Medical implants could fail less often when coated with a microscopically crinkled, ceramic material designed by researchers at the University of Michigan. The coating is described in a paper published in ACS Applied Materials ...

The enemy within: How pathogens spread unrecognized in the body

Some pathogens hide inside human cells to enhance their survival. Researchers at the University of Basel, have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. ...

Key protein regulates immune response to viruses in mammal cells

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development ...

Q&A: The engineer who delivers mRNA inside human cells

Messenger RNA became a household term when it was used as the backbone of the first COVID-19 vaccines, especially after the Nobel Prize was awarded to two mRNA pioneers at the University of Pennsylvania.

Must mRNA be cloaked in a lipid coat to serve as a vaccine?

The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus ...

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