Treating diseases such as Alzheimer's or Parkinson's is a challenge because drugs have to be able to cross the blood–brain barrier. As a result, the doses administered must be high and only a small fraction reaches the ...
Materials Science
Nov 5, 2021
0
153
To understand what role an individual gene plays, biologists have, for 100 years, been using a trick of nature: While in principle, the genome in all cells of an organism is the same, mutations arise in individual cells. ...
Biotechnology
Jun 22, 2021
0
7
Parkinson's disease (PD) is a common neurodegenerative disorder caused by the death of dopaminergic neurons in a part of the brain (known as substantia nigra pars compacta), which leads to a deficit of dopamine (DA), one ...
Bio & Medicine
Jun 1, 2021
0
23
Scientists at the University of Virginia School of Medicine have developed a tool to monitor communications within the brain in a way never before possible, and it has already offered an explanation for why Alzheimer's drugs ...
Bio & Medicine
Mar 9, 2021
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69
Scientists have uncovered an unexpected new role for a protein that may underlie rare diseases.
Cell & Microbiology
Dec 5, 2018
0
57
Computer scientists at Carnegie Mellon University say neural networks and supervised machine learning techniques can efficiently characterize cells that have been studied using single cell RNA-sequencing (scRNA-seq). This ...
Cell & Microbiology
Nov 13, 2018
0
60
A UK-wide research team, led by the University of St Andrews, has developed an innovative new way to optically image through tissue, which could allow for a more detailed understanding and diagnosis of the early stages of ...
Optics & Photonics
Oct 15, 2018
0
119
Many neurodegenerative diseases spread by hijacking the brain's connective circuitry to transport toxic proteins, which gradually accumulate and trigger symptoms of dementias. Now, researchers at Stevens Institute of Technology ...
General Physics
Oct 12, 2018
0
188
Vampires can turn humans into vampires, but to enter a human's house, they must be invited in. Researchers at the UT Southwestern Medical Center, writing in the Journal of Biological Chemistry, have uncovered details of how ...
Biochemistry
Jul 13, 2018
0
148
Researchers studying a protein that causes a hereditary degenerative brain disease in humans have discovered that the human, mouse and hamster forms of the protein, which have nearly identical amino acid sequences, exhibit ...
Biochemistry
Nov 6, 2017
0
11
