A biobank of reversible mutant embryonic stem cells

Scientist at IMBA developed a biobank of revertible, mutant embryonic stem cells, published in the current issue of Nature. This cell bank – called Haplobank - contains over 100,000 mutated, conditional mouse embryonic ...

Which type of cell to become: Decision through indecision

From the moment of fertilization, building a human body involves a series of choices where cells generated by cell division must elect which of the myriad types of cell they will become. How does this decision occur? New ...

Taking a closer look at genetic switches in cancer

Many things go wrong in cells during the development of cancer. At the heart of the chaos are often genetic switches that control the production of new cells. In a particularly aggressive form of leukemia, called acute myeloid ...

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