News tagged with binding site
Related topics: antibodies
The splice of life: Proteins cooperate to regulate gene splicing
Understanding how RNA binding proteins control the genetic splicing code is fundamental to human biology and disease – much like editing film can change a movie scene. Abnormal variations in splicing ...
Feb 16, 2012 |
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A good nose: Researchers decipher interaction of fragrances and olfactory receptors
Banana, mango or apricot - telling these smells apart is no problem for the human nose. How the olfactory organ distinguishes such similar smells has been uncovered by an interdisciplinary team of German researchers at the ...
Chemistry / Analytical Chemistry
Dec 13, 2011 |
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Study finds a weak spot on deadly ebolavirus
Scientists from The Scripps Research Institute and the US Army's Medical Research Institute of Infectious Diseases have isolated and analyzed an antibody that neutralizes Sudan virus, a major species of ebolavirus ...
Nov 21, 2011 |
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How do protein binding sites stay dry in water?
In a report to be published soon in EPJE¹, researchers from the National University of the South in Bahía Blanca, Argentina studied the condition for model cavity and tunnel structures resembling the binding sites ...
Oct 21, 2011 |
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Biologists reveal novel drug binding site in NMDA receptor subunit
Structural biologists at Cold Spring Harbor Laboratory (CSHL) have obtained a precise molecular map of the binding site for an allosteric inhibitor in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which is commonly ...
Jun 16, 2011 |
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Molecular simulations explain how enzymatic pumps transport calcium ions within muscle cells
The transport of ions is essential for the routine maintenance of the body. For this reason cells contain specialized enzymes that act as pumps that help ions to move around and pass through boundaries.
Feb 18, 2011 |
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Direct observation of carbon monoxide binding to metal-porphyrines
What makes carbon monoxide so toxic is that it blocks the binding site for oxygen in hemoglobin. This very mechanism, if better understood, could be used to implement sensors to warn against carbon monoxide. ...
Jan 10, 2011 |
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Can't live without it: The nicotine addiction
The first pull on a cigarette should send you into convulsions. The brain proteins that nicotine affects are nearly identical to a receptor protein on muscle cells that tells them to contract, but nicotine ...
Sep 23, 2010 |
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Team reveals all three structures of single transporter protein
A team of researchers from the Universities of Leeds, Oxford and Imperial College London have captured the 3D atomic models of a single transporter protein in each of its three main structural states, a goal ...
Apr 22, 2010 |
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Key enzyme discovered to be master regulator in protein-protein reactions
Protein phosphorylation is a process by which proteins are flipped from one activation state to another. It is a crucial function for most living beings, since phosphorylation controls nearly every cellular ...
Mar 24, 2010 |
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Chemists discover how antiviral drugs bind to and block flu virus
Antiviral drugs block influenza A viruses from reproducing and spreading by attaching to a site within a proton channel necessary for the virus to infect healthy cells, according to a research project led ...
Feb 03, 2010 |
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Mirror images united: Simultaneous binding of both enantiomers of a drug to an enzyme
(PhysOrg.com) -- In the binding pockets of enzymes their natural binding partners fit exactly. The principle by which many pharmacological agents work also relies on the fact that these substances fit exactly into the pockets ...
Oct 29, 2009 |
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Scorpion venom with nanoparticles slows spread of brain cancer
By combining nanoparticles with a scorpion venom compound already being investigated for treating brain cancer, University of Washington researchers found they could cut the spread of cancerous cells by 98 ...
Nanotechnology / Bio & Medicine
Apr 16, 2009 |
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