An LMU team has shown that orthosomycins bind to a site on the bacterial ribosome that is not used by any other antibiotic. The finding could lead to agents that are effective against existing multi-drug resistant bacterial ...
Cell & Microbiology
Jul 15, 2016
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Researchers at ETH Zurich are decoding the structure of the large ribosomal subunit of the mitochondria at an atomic level, thereby providing insight into the molecular architecture of this ribosome with implications for ...
Biochemistry
Oct 8, 2014
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(Phys.org) —A groundbreaking study of the human ribosome is revealing that the tiny molecular machine is more versatile than previously understood. Minor changes in its sequencing can change its operation, allowing it to ...
Cell & Microbiology
Jul 4, 2014
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When cells grow and proliferate, they need to produce large amounts of protein. All this protein is made by ribosomes, therefore rapid growth requires many ribosomes. Because ribosomes are expensive machines for the cell, ...
Cell & Microbiology
Oct 15, 2013
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(Phys.org) —This may look like a tangle of squiggly lines, but you're actually looking at a molecular machine called a ribosome. Its job is to translate DNA sequences into proteins, the workhorse compounds that sustain ...
Cell & Microbiology
Jun 28, 2013
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The overuse of antibiotics has created strains of bacteria resistant to medication, making the diseases they cause difficult to treat, or even deadly. But now a research team at the University of Rochester has identified ...
Cell & Microbiology
Feb 26, 2013
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(Phys.org)—Scientists are unsure why proteins form improperly and cluster together in bunches, a hallmark of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's and Mad Cow Disease. In the ...
Cell & Microbiology
Nov 2, 2012
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A recent study into the interactions between aminoglycoside antibiotics and their target site in bacteria used computer simulations to elucidate this mechanism and thereby suggest drug modifications.
Cell & Microbiology
Jul 21, 2011
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A new "tree of life" has been constructed by researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech for the gamma-proteobacteria, a large group of medically and scientifically important bacteria that ...
Biotechnology
May 17, 2010
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The organelles of photosynthesis—the chloroplasts - have their own DNA, messenger RNA and ribosomes for forming proteins. Max Planck scientists have now discovered how to regulate the formation of proteins in the chloroplasts. ...
Biotechnology
Mar 30, 2010
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