Veterinarians diagnose rare autoimmune disease, put dog on road to recovery
Having two autoimmune diseases is unusual for a dog, but having three is exceptionally rare.
Having two autoimmune diseases is unusual for a dog, but having three is exceptionally rare.
Veterinary medicine
Mar 28, 2024
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Autoimmune diseases are mysterious. It wasn't until the 1950s that scientists realized that the immune system could harm the organs of its own body. Even today, the fundamental causes and inner workings of most autoimmune ...
Bio & Medicine
Mar 21, 2024
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110
Women are far more likely than men to get autoimmune diseases, when an out-of-whack immune system attacks their own bodies—and new research may finally explain why.
Molecular & Computational biology
Feb 3, 2024
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23
A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome"—the 98% of our DNA that has largely unknown biological function. These results ...
Biotechnology
Dec 14, 2023
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160
Autoimmune disorders are among the most prevalent chronic diseases across the globe. Emerging treatments for autoimmune disorders focus on "adoptive cell therapies," or those using cells from a patient's own body to achieve ...
Bio & Medicine
Nov 14, 2023
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65
When targeting problem proteins involved in causing or spreading disease, a drug will often clog up a protein's active site so it can't function and wreak havoc. New strategies for dealing with these proteins can send these ...
Cell & Microbiology
Oct 25, 2023
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32
Diagnosing and treating gastrointestinal tract diseases can be notoriously invasive and time-consuming: blood and stool lab work; biopsies, colonoscopies and endoscopies; and X-rays, CT scans and MRI imaging. But what if ...
Bio & Medicine
May 29, 2023
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71
Peanut allergies affect 1 in 50 children, and the most severe cases lead to a potentially deadly immune reaction called anaphylactic shock.
Bio & Medicine
Apr 3, 2023
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143
Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.
Cell & Microbiology
Mar 30, 2023
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20
Up to 50% of cancer-signaling proteins once believed to be immune to drug treatments due to a lack of targetable protein regions may actually be treatable, according to a new study from the Perelman School of Medicine at ...
Biotechnology
Mar 22, 2023
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40
Autoimmunity is the failure of an organism to recognize its own constituent parts as self, which allows an immune response against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Autoimmunity is often caused by a lack of germ development of a target body and as such the immune response acts against its own cells and tissues. Prominent examples include Coeliac disease, diabetes mellitus type 1 (IDDM), systemic lupus erythematosus (SLE), Sjögren's syndrome, Churg-Strauss Syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, rheumatoid arthritis (RA), lupus and allergies. Autoimmune diseases are very often treated with steroids.
The misconception that an individual's immune system is totally incapable of recognizing self antigens is not new. Paul Ehrlich, at the beginning of the twentieth century, proposed the concept of horror autotoxicus, wherein a 'normal' body does not mount an immune response against its own tissues. Thus, any autoimmune response was perceived to be abnormal and postulated to be connected with human disease. Now, it is accepted that autoimmune responses are an integral part of vertebrate immune systems (sometimes termed 'natural autoimmunity'), normally prevented from causing disease by the phenomenon of immunological tolerance to self-antigens. Autoimmunity should not be confused with alloimmunity.
This text uses material from Wikipedia, licensed under CC BY-SA