Simulating amyloid formation

Many neurodegenerative diseases are characterized by proteins that assume an abnormal configuration, which leads to their aggregation and deposition in and around rve cells, causing cell death. This process, called amyloid ...

Pulmonary fibrosis inhibited by pentraxin-2/SAP in research study

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today the publication of collaborative research in the International Journal of Biochemistry ...

Unlocking the secret(ase) of building neural circuits

Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease -- early-onset familial Alzheimer's -- which can strike people as early as their 30s. In their latest study, researchers at the ...

New therapy targets for amyloid disease

A major discovery is challenging accepted thinking about amyloids - the fibrous protein deposits associated with diseases such as Alzheimer's and Parkinson's - and may open up a potential new area for therapeutics.

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