New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...
Biochemistry
Dec 5, 2022
0
15
Researchers at Leipzig University have solved a puzzle in the evolution of bacterial enzymes. By reconstructing a candidate for a special RNA polymerase as it existed about 2 billion years ago, they were able to explain a ...
Evolution
Dec 5, 2022
0
567
Nucleobase-containing coenzymes are believed to be the relics of an ancient RNA world and can provide information on the origin and evolution of proteins. However, coenzyme-protein interactions largely remain unclear.
Biochemistry
Nov 25, 2022
0
20
When humans get hurt, they feel pain. Between these occurrences there is a series of indirect relay reactions. An analogical set called transduction of signals exists in all living organisms, including plants. When a stimulus ...
Plants & Animals
Nov 18, 2022
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17
You can't move a pharmaceutical scientist from a lab to a kitchen and expect the same research output. Enzymes behave exactly the same: They are dependent upon a specific environment. But now, in a study recently published ...
Biotechnology
Nov 3, 2022
0
174
Vikas Nanda has spent more than two decades studying the intricacies of proteins, the highly complex substances present in all living organisms. The Rutgers scientist has long contemplated how the unique patterns of amino ...
Biochemistry
Nov 2, 2022
0
82
Over the last decade, the lush olive groves one associates with the Italian countryside have become desiccated, as if stuck in a perpetual winter. The culprit is Xylella fastidiosa, a species of aggressive bacteria that have ...
Plants & Animals
Oct 24, 2022
0
3
Mitochondria—the organelles responsible for energy production in human cells—were once free-living organisms that found their way into early eukaryotic cells over a billion years ago. Since then, they have merged seamlessly ...
Cell & Microbiology
Oct 20, 2022
0
69
An international team of scientists, including from the Universities of Bristol and Oxford, and the Natural History Museum, have discovered that a well-preserved, fossilized worm dating from 518 million years ago resembles ...
Evolution
Sep 27, 2022
0
430
Researchers have discovered a new way hospital-acquired infections resist antibiotics, through a "silent" genetic mutation.
Cell & Microbiology
Sep 19, 2022
0
71
