Researchers from Facebook AI Research (FAIR) at Meta AI have published a paper in the journal Science detailing a machine-learning-created database of 617 million predicted protein structures. The ESMFold language model described ...
The faba bean genome, which at 13 billion bases is more than four times the size of the human genome, has been sequenced for the first time and is published in Nature. This is an extraordinary technical achievement and crucial ...
Molecular & Computational biology
Mar 8, 2023
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33
Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have discovered a mechanism involving ribosomes which helps the heart toggle between a 'regular maintenance mode' for day-to-day function and an 'energy-boost ...
Cell & Microbiology
Mar 7, 2023
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43
ATP, the compound essential for the functioning of photosynthetic organisms such as plants, algae, and cyanobacteria, is produced by an enzyme called "chloroplast ATP synthase" (CFoCF1). To control ATP production under varying ...
Plants & Animals
Feb 22, 2023
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266
Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs.
Molecular & Computational biology
Jan 31, 2023
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237
Watching a puppet show can teach you something about how estrogen works in the body, according to Rice University scientists whose research could open the door to new strategies for regulating the hormone—which could ...
Biochemistry
Jan 30, 2023
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69
Scientists have created an AI system capable of generating artificial enzymes from scratch. In laboratory tests, some of these enzymes worked as well as those found in nature, even when their artificially generated amino ...
Biotechnology
Jan 26, 2023
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242
Researchers have visualized the protein binding site of the (pro)renin receptor known to be involved in pancreatic cancer development using an artificial intelligence-based protein structure prediction program. They predicted ...
Cell & Microbiology
Dec 9, 2022
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40
Antimicrobial resistance (AMR) is a global health problem. Species of drug-resistant pathogens, including Neisseria gonorrhoeae, could become untreatable due to a high degree of AMR.
Biochemistry
Dec 9, 2022
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52
New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...
Biochemistry
Dec 5, 2022
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