Actin cytonauts at play in the cell
Scientists uncover the nuclear life of actin
A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.
Unlocking long-hidden mechanisms of plant cell division
Along with copying and splitting DNA during division, cells must have a way to break safely into two viable daughter cells, a process called cytokinesis. But the molecular basis of how plant cells accomplish ...
Researchers uncover secrets of internal cell fine-tuning
New research from scientists at the University of Kent has shown for the first time how the structures inside cells are regulated – a breakthrough that could have a major impact on cancer therapy development.
Atomic structure of key muscle component revealed
Actin is the most abundant protein in the body, and when you look more closely at its fundamental role in life, it's easy to see why. It is the basis of most movement in the body, and all cells and components ...
Researchers develop new model of cellular movement
(Phys.org) —Cell movement plays an important role in a host of biological functions from embryonic development to repairing wounded tissue. It also enables cancer cells to break free from their sites of ...
Building the ring to divide them all: Septin proteins bundle actin filaments into a ring
Researchers of the FOM Institute AMOLF and from Marseille and Paris have demonstrated that cells require a protein called septin to build a ring of actin filaments. This ring of proteins is crucial to drive ...
Cytoskeletons get a closer look
(Phys.org) —Rice University researchers have developed a theoretical approach to analyze the process by which protein building blocks form the biopolymer skeletons of living cells.
Mitosis mystery solved as role of key protein is confirmed
Researchers from Warwick Medical School have discovered the key role of a protein in shutting down endocytosis during mitosis, answering a question that has evaded scientists for half a century.
Gravity plays a role in keeping cells small
(Phys.org) —The effects of gravity are relevant when building houses or flying airplanes, but biologists have generally accepted that the average cell is too small for gravity to play a role in how it is ...
Researchers define role of protein vinculin in cell movement
Researchers at the University of North Carolina and the National Institutes for Health have defined the role of the protein vinculin in enabling cell movement.
Scientists find long-sought method to efficiently make complex anticancer compound
Scientists at The Scripps Research Institute (TSRI) have achieved the first efficient chemical synthesis of ingenol, a highly complex, plant-derived compound that has long been of interest to drug developers ...
Team charts new understanding of actin filament growth in cells
University of Oregon biochemists have determined how tiny synthetic molecules disrupt an important actin-related molecular machine in cells in one study and, in a second one, the crystal structure of that ...
Biceps bulge, calves curve, 50-year-old assumptions muscled aside
The basics of how a muscle generates power remain the same: Filaments of myosin tugging on filaments of actin shorten, or contract, the muscle – but the power doesn't just come from what's happening straight ...