Local modifications in histone proteins alter DNA packing density in the cell nucleus to regulate gene activity. They also form the basis of a code in which the significance of a given pattern or motif depends on its broader ...
Biotechnology
Jan 28, 2016
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In a new study, scientists at the National Institutes of Health took a molecular-level journey into microtubules, the hollow cylinders inside brain cells that act as skeletons and internal highways. They watched how a protein ...
Cell & Microbiology
Jun 13, 2014
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One of biology's most fundamental processes is something called transcription. It is just one step of many required to build proteins—and without it life would not exist. However, many aspects of transcription remain shrouded ...
Cell & Microbiology
Nov 7, 2013
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A study investigating the function of the recently discovered enhancer RNA molecules may open new avenues for gene therapy. According to the study researchers, altering the production and function of these molecules could ...
Cell & Microbiology
Aug 13, 2013
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Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms underlying this ...
Cell & Microbiology
Oct 5, 2012
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In 1925, Henry Ford observed that fuel is present in all vegetative matter that can be fermented and predicted that Americans would some day grow their own fuel. Last year, global biofuel production reached 28 billion US ...
Biotechnology
Nov 16, 2011
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Lowly bacteria are turning out to be much more complex than previously thought.
Cell & Microbiology
Jul 12, 2010
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The kinase IKK phosphorylates the protein mutated in Huntington's disease to promote its removal and neuron survival, but IKK may be a double-edged sword that increases neurotoxicity in later stages of the disease. The study, ...
Cell & Microbiology
Dec 21, 2009
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Johns Hopkins researchers have discovered a new energy-making biochemical twist in determining the lifespan of yeast cells, one so valuable to longevity that it is likely to also functions in humans.
Cell & Microbiology
Mar 24, 2009
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