A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.
Cell & Microbiology
Oct 29, 2015
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57
A process called sporulation that helps the dangerous bacterium Clostridium difficile (C. difficile) to survive inhospitable conditions and spread is regulated by epigenetics, factors that affect gene expression beyond the ...
Cell & Microbiology
Nov 25, 2019
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118
Mutations that disrupt development of germ cells cause infertility or birth defects. Mutations that cause female infertility in humans, such as mutations in the gene BMP15, also cause infertility in zebrafish. However, female ...
Cell & Microbiology
Jan 22, 2024
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45
Using a novel proteogenomic strategy and a variety of machine learning tools, investigators from the Icahn School of Medicine at Mount Sinai and colleagues have identified a 64-protein signature that may predict a subset ...
Cell & Microbiology
Aug 3, 2023
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14
Blood-forming stem cells found in bone marrow are the life-saving component used in bone marrow transplants. However, suitable donors cannot be found in many cases. A new study reveals how the human embryo develops the precursor ...
Cell & Microbiology
Apr 28, 2022
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67
A skull is not one single bone but rather a collection of bone plates joined together early in development. In a study of mice, scientists at the Icahn School of Medicine at Mount Sinai showed how the activity of one gene, ...
Cell & Microbiology
Dec 9, 2021
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71
A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19. The discovery could lead to the design of critically ...
Molecular & Computational biology
Sep 8, 2022
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65
As microRNA biology has been implicated in everything from the development of cancer to virus infections, a new tool developed by scientists at the Icahn School of Medicine at Mount Sinai holds tremendous potential to develop ...
Cell & Microbiology
Dec 9, 2015
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6
A research team headed by investigators at the Icahn School of Medicine at Mount Sinai (ISMMS) has developed a tool that allows scientists to quickly manipulate levels of two proteins in the same cell. They say the method, ...
Cell & Microbiology
Aug 4, 2016
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6
Some heritable but unstable genetic mutations that are passed from parent to affected offspring may not be easy to investigate using current human-induced pluripotent stem cell (hiPSC) modeling techniques, according to research ...
Cell & Microbiology
Mar 13, 2017
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