Rockefeller University

Tracking down the origin of leukemia relapse

The cancer cells that reign during relapses of an aggressive human leukemia are different from those that dominated the original disease, according to a paper published online on April 4 in the Journal of Experimental Me ...

Apr 04, 2011
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Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of ...

Dec 29, 2008
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'Birth control' for centrioles

Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that ...

Jan 26, 2009
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With HMGB1's help, cells dine in

Like some people, cells eat when they are under pressure -- but they consume parts of themselves. A multi-function protein helps control this form of cannibalism, according to a study in the September 6 issue ...

Sep 06, 2010
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