Rockefeller University

Matrix fragments trigger fatal excitement

Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of ...

Dec 29, 2008 5 / 5 (4) 0

'Birth control' for centrioles

Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that ...

Jan 26, 2009 4 / 5 (2) 0

With HMGB1's help, cells dine in

Like some people, cells eat when they are under pressure -- but they consume parts of themselves. A multi-function protein helps control this form of cannibalism, according to a study in the September 6 issue ...

Sep 06, 2010 not rated yet 0

FHL1 helps build muscle mass

Cowling et al. report how to build muscle mass with FHL1. The protein partners with and activates the transcription factor, NFATc1. Encouraging this partnership might provide a possible treatment for muscle ...

Dec 15, 2008 2.5 / 5 (2) 0