The Friedrich Miescher Institute for Biomedical Research (FMI) is part of the Novartis Research Foundation and is a world-class center for basic research in life sciences based in Basel, Switzerland. The FMI is devoted to the pursuit of fundamental biomedical research. Areas of expertise are: In these fields the FMI has gained international recognition as a center of excellence in innovative biomedical research. Research is carried out in 22 independent but highly interactive research teams. In addition, seven technology platforms, ranging from functional genomics to microscopy and imaging, support the research activities with cutting-edge technology. As of 2011, the institute counts 320 collaborators of which 90 are postgraduate students participating in the FMI International PhD Program, 100 are postdoctoral collaborators and 22 are research group leaders. Since 2004, the institute is led by Susan M. Gasser. in chronological order The FMI is an affiliated institute of the University of Basel. It provides biomedical research and career training for over 90 PhD students. FMI selects its highly international student body during a twice-yearly interview-based selection program.
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Regenerating damaged tissues or organs has been a dream of scientists for decades. Now, researchers at the FMI and Novartis Biomedical Research have discovered a new molecule that activates a protein involved in regeneration. ...
Biotechnology
Apr 23, 2024
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Gene expression is controlled by numerous small RNA molecules called microRNAs, or miRNAs. However, specific functions of most miRNAs remain poorly understood. Working with worms, Friedrich Miescher Institute (FMI) researchers ...
Molecular & Computational biology
Feb 22, 2024
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32
Influenza and other viruses pack their genetic material into a protein shell, which must be disassembled for the viruses to efficiently replicate. But how viruses "uncoat" their genes remains largely unknown. Now, Friedrich ...
Cell & Microbiology
Jan 3, 2024
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3
The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA repair, cell division and ...
Molecular & Computational biology
Jun 30, 2023
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50
Scientists have known that when a mouse embryo is developing, the cells that will become its spine and muscles switch specific genes on and off repeatedly, in a synchronous fashion. However, there are deep mysteries about ...
Cell & Microbiology
May 2, 2023
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222
New work by Friedrich Miescher Institute researchers shows that key proteins help to stabilize the interaction between otherwise highly dynamic DNA structures. The findings shed light onto how the complex folds that help ...
Cell & Microbiology
Dec 6, 2022
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Even small differences in how fast animals grow during development can sum up to large differences in their adult body size. Nevertheless, adults of the same species are usually nearly identical in size. Benjamin Towbin, ...
Plants & Animals
Jun 7, 2022
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44
FMI researchers have identified a synthetic protein that dampens the activity of a cellular pathway involved in viral infection. The findings could help to develop drugs that combat viruses such as influenza A and Zika.
Cell & Microbiology
May 11, 2022
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117
Cilia, the little "hairs" attached to almost all cells of the human body, play a role in various cellular functions and cause diseases called ciliopathies when they are defective. Researchers from the group of Patrick Matthias ...
Molecular & Computational biology
Apr 20, 2022
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55
Our actions are motivated by the goals we want to achieve. However, little is known about the mechanism in our brains that allow us to make the right decisions to reach our goals. Researchers in the Lüthi lab now identified ...
Plants & Animals
Jan 7, 2022
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