'Silver nanoparticle' microscope may shed new light on cancer, bone diseases

Feb 26, 2009

In a finding that could help speed the understanding of diseases ranging from cancer to osteoporosis, researchers in Utah are reporting development of a new microscope technique that uses “silver nanoparticle” mirrors to reveal hidden details inside bones, cancer cells, and other biological structures. The method also can help identify structural damage in a wide variety of materials, including carbon-fiber plastics used in airplanes, the researchers say.

Their study is scheduled for the March issue of ACS’ Nano Letters.

In the new study, John Lupton and colleagues point out that one of the most powerful, widely used tools for imaging hidden biological structures is fluorescence microscopy, which requires the specimen to be treated with fluorescent dyes or stains. But the dyes used to visualize the structures can kill living cells, limiting the effectiveness of the technique, the researchers note.

The scientists improved on this technique by using an infrared laser to excite clusters of silver nanoparticles, each about 1/5000th the width of a human hair, placed below the material being studied. The particles focus intense beams of light up through the sample to reveal information about the composition and structure of the substance examined, the scientists say. In laboratory studies, they used the new technique to view the iridescent green scales of the so-called “photonic beetle,” whose scales may provide clues to designing new, more powerful solar cells and computer chips, the scientists say.

Provided by ACS

Explore further: Gold nanorods target cancer cells

add to favorites email to friend print save as pdf

Related Stories

Chemists crack the chirality code

Dec 12, 2014

Chemists at Trinity College Dublin have cracked the chirality code. The chirality (or left/right-handed asymmetry) of amino acids presented a long-standing challenge that complicated efforts to create certain types of proteins, ...

Nanoshaping method points to future manufacturing technology

Dec 11, 2014

A new method that creates large-area patterns of three-dimensional nanoshapes from metal sheets represents a potential manufacturing system to inexpensively mass produce innovations such as "plasmonic metamaterials" for advanced ...

Recommended for you

Gold nanorods target cancer cells

12 hours ago

Using tiny gold nanorods, researchers at Swinburne University of Technology have demonstrated a potential breakthrough in cancer therapy.

User comments : 0

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.