Neural qubits: Quantum cognition based on synaptic nuclear spins

August 27, 2015 by John Hewitt report
Neural qubits: quantum cognition based on synaptic nuclear spins
Posner Clusters. Credit: Lijun Wang et al. Huazhong Agricultural University, ugr.es/~grupo179/pdf/Wang%202012b.pdf

(Phys.org)—The pursuit of an understanding of the base machinery of the mind led early researchers to anatomical exhaustion. With neuroscience now in the throes of molecular mayhem and a waning biochemical bliss, physics is spicing things up with a host of eclectic quantum, spin, and isotopic novelties. While increases in electron spin content have been linked to anesthetic effects, nuclear spins have recently been implicated in a more rarefied and subtle phenomenon— neural quantum processing.

Matthew Fisher from University of California at Santa Barbara has hashed out one scenario by which it all could work in a new paper now on the Arxiv server. He notes that while small molecules and ions would rapidly entangle with a surrounding wet environment and therefore couldn't maintain on macroscopic time scales, are exceptional in being so weakly coupled to environmental degrees of freedom that prolonged phase coherence is likely.

How long, you might ask? That depends which element you are talking about, and the quantum value of its spin. Every element has a nucleus that can be characterized by half-integer spin-magnitude (I = 0; 1=1/2; 1...). Quantum decoherence of the nuclear spin is caused by magnetic and electric field perturbations which effectively kill any hope for quantum processing. Fisher claims that the element with the optimal coherence time (Tcoh), and therefore the one ideally poised to host the putative neural qubit should have nuclear spin of 1/2. In a biochemical setting, spin 1/2 nuclei are weakly decohered only by magnetic fields while for spin >1/2 electric fields cause large decoherence. Spin 0 nuclei lack any associated magnetic dipole moment interaction with nuclear magnetic fields

Fisher's interest in neural nuclear spin processing was stimulated by a paper that explored the effects of different isotopes of lithium on rats. Li naturally occurs in the ratio 92.6% Li-7 and 7.4% Li-6. Somewhat quizzically, mothers given the Li-7 isotope were less stimulated and ignored their pups while the Li-6 moms were maternalistic and nursed more. The interesting part for us here, is that while Li-7 has spin 3/2 and a short Tcoh of just a few seconds, Li-6 has an "honorary" spin 1/2 due to its electric dipole moment and a nice 5 minute long Tcoh.

Since Li isn't common to most life, and because phosphorus is the only common biochemical element that has spin 1/2, Fisher focused on organophosphates. These are the various common esters of inorganic phoshopate ions (Pi) like ATP and poly-phosphate chains (PPi). Although these froms of phosphate have a Tcoh on the order of a second and might serve as effective neural qubit transporters in the right context, Fisher theorized that a form of phosphate known as a Posner molecule might better serve for qubit memory storage. If calcium displaces the proton in phosphate ions, Posner clusters of Ca9(PO4)6 have significantly longer Tcoh times (potentially days) can form. Previous x-ray diffraction studies have even suggested that amorphous calcium phosphate Posner clusters could be a key step in the mineralization of bone into hydroxyapaptite crystal.

The present discussion of regarding curious phosphate phenomena does not pop out fully-formed from in its own void. There is an ample if occaisionally controversial body of experimental findings dealing with magnetic isotope and field effects on the major phosphorylation reactions of life Regarding the enzyme catalyzed hydrolysis reaction of PPi into Pi + Pi, Fisher outlines a scenario whereby reaction rate is dependent on the nuclear spin state, ie. different for the singlet and triplet states. To pool ideas together under the rubric of actually performing quantum processing, some form of quantum entanglement and subsequent measurement is needed.

To get there we need to imagine entangled phosphate pairs released into extracellular fluid, as at a synapse, where they can combine with calcium ions to form multiple Posner molecules that in effect hold entangled phosphorus spins in memory. The magic happens if and when Posner molecules bind after being transported into two separate presynaptic terminals. At that point, the paper claims, they would be suseptible to melting in the acidified interior of the vesicle through which they entered, with subsequent synaptic calcium dynamics and entangled postsynaptic firing. The stability of Posner molecules appears to be exquisitely pH-sensitive in bone, and by implication elsewhere. Binding (into dimers and higher order clusters) affects their ability to displace surrounding water molecules and rotate through different symmetry axes, which correspondingly affects the rate at which protons can attack and melt them.

The details of all this hinge on, or are at least theorized to benefit from the particular qualities of the vesicle-based transporters installed on glutamatergic synapses. Originally discovered as sodium-dependant bit kidney phosphate transporters, sequence homology studies found similar transporters (VGLUTs) at the presynapse that act in a pH-dependant fashion to fill vesicles with glutamte. Fisher proposes that these VGLUTs have dual role first in taking up presumptive Posner molecules during brief exposures of the fusion pore during classical exocytosis, and then later operate much in reverse to express decomposed phosphorus into the larger presynaptic space. Thereafter, at least in briefly talking to Fisher, the potential exists to reform Posner clusters here, which can in turn re-melt with each generating 18 calcium ions to contribute to transmitter release.

VGLUTs themselves come in different forms and future work may help identify their respective roles. Other esoteric phenomena are undoubtedly also involved at a deep level in synaptic function, and one need not look to far abroad to find hint of them. For example, we previously proposed a potential mechanism where these pH-dependant glutamate transporters play a role in recently reported neural shock wave events in order to generalize the observation from acetylcholinergic synapses to other amino acid-based transmitter systems.

In the meantime, Fisher intends to re-explore the older Li isotope work and further refine the mechanisms and any potential shortfalls of the Posner conception. As alluded to above, electron spin itself is still a relatively obscure concept in biology save for a few niche revelations on things like chemical compasses or other radical pair-pair inspired biologics. Yet free radicals (unpaired electron spins) have a magnetic moment 1,000 or so times larger than that of a proton. Their presence alone could be a significant factor in things like phosphorus nuclear spin decoherence.

Explore further: Quantum computing: Manipulating a single nuclear spin qubit of a laser cooled atom

More information: Quantum Cognition: The possibility of processing with nuclear spins in the brain, arXiv:1508.05929 [q-bio.NC] arxiv.org/abs/1508.05929

Abstract
The possibility that quantum processing with nuclear spins might be operative in the brain is proposed and then explored. Phosphorus is identified as the unique biological element with a nuclear spin that can serve as a qubit for such putative quantum processing - a neural qubit - while the phosphate ion is the only possible qubit-transporter. We identify the "Posner molecule", Ca9(PO4)6, as the unique molecule that can protect the neural qubits on very long times and thereby serve as a (working) quantum-memory. A central requirement for quantum-processing is quantum entanglement. It is argued that the enzyme catalyzed chemical reaction which breaks a pyrophosphate ion into two phosphate ions can quantum entangle pairs of qubits. Posner molecules, formed by binding such phosphate pairs with extracellular calcium ions, will inherit the nuclear spin entanglement. A mechanism for transporting Posner molecules into presynaptic neurons during a ``kiss and run" exocytosis, which releases neurotransmitters into the synaptic cleft, is proposed. Quantum measurements can occur when a pair of Posner molecules chemically bind and subsequently melt, releasing a shower of intra-cellular calcium ions that can trigger further neurotransmitter release and enhance the probability of post-synaptic neuron firing. Multiple entangled Posner molecules, triggering non-local quantum correlations of neuron firing rates, would provide the key mechanism for neural quantum processing. Implications, both in vitro and in vivo, are briefly mentioned.

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nilbud
3 / 5 (6) Aug 27, 2015
Roger Penrose will be pleased.
Egleton
2 / 5 (4) Aug 27, 2015
Indeed he will. And so am I. Not that I put myself at the same table as Sir Roger. But it strikes me as obvious that evolution would make use of Entanglement. Further, where else would you expect to find Mind but in the information field ?
Let me prognosticate. We will find to our surprise that our first quantum computers are sentient.
Spin Brain
5 / 5 (1) Aug 27, 2015
The idea of nuclear spin being involved conscious experience and neural memory was put forward back in 2002 in Spin Mediated Consciousness Theory by Huping Hu and Maoxin Wu.
johnhew
3.7 / 5 (3) Aug 27, 2015
I see, quite fantastical, Russian polywater gone full voodoo doll, 'We further found that drinking water exposed to magnetic pulses, laser light or microwave when an anaesthetic was placed in between also causes brain effects in various degrees'
http://arxiv.org/...68v5.pdf
barakn
3 / 5 (2) Aug 27, 2015
Johnhew, read the paper, the study was done blind but not double-blind, and hence the results are highly suspect.
johnhew
1 / 5 (3) Aug 27, 2015
The lithium paper? I don't believe any paper, even one with a triple blind study.
JVK
1 / 5 (5) Aug 28, 2015
Thanks for helping to put quantum consciousness into the perspective of phosphorylation.

With others, Gene Robinson tentatively linked phophorylation from Luca Turin's quantum smell to nutrient-dependent pheromone-controlled RNA-mediated cell type differentiation with this simple statement from: "Intronic Non-CG DNA hydroxymethylation and alternative mRNA splicing in honey bees" Excerpt: "The authors present evidence that argues that alternative splicing is used to alter protein phosphorylation, which can alter protein stability, subcellular localization, activity, and other properties [45]." http://www.biomed...4/14/666

In the honeybee model organism of human behavior, altered stability of proteins and epigenetically-effected organized genomes is obviously biophysically constrained by the chemistry of RNA-mediated cell type differentiation in the context of fixed amino acid substitutions that ensure species survival.
JVK
1 / 5 (5) Aug 28, 2015
I don't believe any paper, even one with a triple blind study.


I believe papers need to be integrated into a model that links atoms to ecosystems via what is known about biophysically constrained nutrient-dependent protein folding and RNA-mediated cell type differentiation in the context of fixed amino acid substitutions that ensure species survival.

Others, see for example: Nutrient-dependent/pheromone-controlled adaptive evolution: a model. http://www.ncbi.n...24693353

Excerpt: "The honeybee already serves as a model organism for studying human immunity, disease resistance, allergic reaction, circadian rhythms, antibiotic resistance, the development of the brain and behavior, mental health, longevity, diseases of the X chromosome, learning and memory, as well as conditioned responses to sensory stimuli (Kohl, 2012)."

It is safer to assume that the honeybee model organism links cause and effect than to assume anything about mutations.
JVK
1 / 5 (5) Aug 28, 2015
Roger Penrose will be pleased.


What does that mean outside the context of the anti-entropic energy of sunlight that Schrodinger linked to nutrient-dependent biologically-based cell type differentiation? Has Penrose ever commented on the epigenetic traps that are required to link sunlight and phosphorylation?

Would any evolutionary theorist or philosopher be pleased to learn that they have missed learning about everything known to serious scientists about how neural qubits and chemical ecology may link (1) ecological niche construction, (2) social niche construction, (3) neurogenic niche construction, and (4) socio-cognitive niche construction?

Roger Penrose will be pleased.


That is the kind of nonsensical comment that people will use to claim that others have known all along how to link atoms to ecosystems, but have instead reported their findings in the language of theoretical physics and neo-Darwinian evolutionary theory.

Vietvet
4.2 / 5 (5) Aug 28, 2015
Criticisms of the nutrient-dependent pheromone-controlled ...
www.ncbi.nlm.nih.gov/...
National Center for Biotechnology Information

http://www.ncbi.n...4049134/
JVK
1 / 5 (5) Aug 28, 2015
See also: Life's a Gas: A Thermodynamic Theory of Biological Evolution http://www.mdpi.c...7/8/5522

What is currently known to serious scientists about top-down causation continues to force the pseudoscientific nonsense out of theories, as the pseudoscientists who tout them fight back.

Mutations must be the anti-entropic force that links natural selection to evolution if ecological variation is not linked to ecological adaptations via biophysically constrained nutrient-dependent RNA-mediated protein folding chemistry and the conserved molecular mechanisms that link the physiology of reproduction to all biomass on this planet via the speed of light when it is slowed on contact with water.

Thus, de Vries definition of "mutation" can still be used in misrepresentations of biologically-based cause and effect that begin with ecological variation and link atoms to ecosystems via the physiology or reproduction in all living genera.
JVK
1 / 5 (5) Aug 28, 2015
The idea of nuclear spin being involved conscious experience and neural memory was put forward back in 2002...
-- Spin Brain

See also: http://www.quantu...ides.pdf Spin-mediated consciousness theory: possible roles of neural membrane nuclear spin ensembles and paramagnetic oxygen http://www.scienc...04002440

Would someone try to explain how spin is linked to the de novo creation of genes that are required to link ecological variation to ecological adaptations in the context of any atoms to ecosystems model of quantum physics linked to quantum consciousness via these two model organisms, or any other model organism?

Electron spin changes during general anesthesia in Drosophila http://www.ncbi.n...4151765/

Dose-Dependent Effects of the Clinical Anesthetic Isoflurane on Octopus vulgaris
http://www.tandfo...4.945047
docile
Aug 28, 2015
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docile
Aug 28, 2015
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Captain Stumpy
5 / 5 (4) Aug 28, 2015
de Vries definition of "mutation" can still be used
@jk
only by someone who FAILED out of college and is promoting pseudoscience!

there is a VERY specific meaning to the word "mutation" that is found in the lexicon of the biological/medical field, and it is repeated and posted in the professional terminology/lexicon that are specific to the field
which is WHY you don't know the meaning!
-you are a lowly lab tech who refuses to even educate himself with the terminology of the field you profess expert knowledge in! that is why you've continually lied about your "experience" and abilities (can you say: Mensa?) because you think it adds credibility to your argument

credibility is gained by presenting FACTS backed by empirical evidence, NOT PSEUDOSCIENCE CREATIONIST IDEALS or opinion backed by your "say-so"

if you want to know what the word means, use the dictionary- NIH has a published web version, and so does MIT
USE IT
JVK
1 / 5 (5) Aug 28, 2015
...even strong magnetic field doesn't harm the thinking of brain, which would do it, if the nuclear spins would be involved.


This forces me to ask if biologically uniformed science idiots understand anything about the stability of organized genomes in the context of ecological adaptations.

Captain Stumpy
5 / 5 (4) Aug 28, 2015
via the speed of light when it is slowed on contact with water
you have repeatedly said that
In the past two years I've learned enough about physics to link the speed of light on contact with water to the de novo creation of amino acids
but you have YET to be able to actually produce ANY evidence, let alone reputable evidence
Why do you keep trying to promote a physics phenomenon? especially one that would have garnered you a Nobel almost instantly?

As Vietvet has shown, your "model" is debunked
http://www.ncbi.n...4049134/

you still can't figure out why your model is treated with scorn because of your anti-mutation crusade... which is funny considering YOUR OWN MODEL requires them!
and you even ADMIT to it!
shall i repost that little gem? because i also provided you with 3 different resources for the definition of mutation which proved you post PSEUDOSCIENCE

jk=troll
Captain Stumpy
5 / 5 (4) Aug 28, 2015
This forces me to ask if biologically uniformed science idiots understand anything about the stability of organized genomes in the context of ecological adaptations.
well, we KNOW that you do not!

this is evident in your 100% FAIL rate interpreting science... from Lenski to Whittaker and more...

otherwise you would understand WHY Lenski's experiments debunk your "mutations perturb protein folding & are always pathological" comments

care to try for the physics you FAIL at above?
what about your insistence that various authors support your claims... that is, until they debunk your claims... then they all become "biologically uniformed science idiots"... you know, like your claims about Extavour, Whittaker and Lenski? as well as every other Biologist/medical professional out there?
JVK
1 / 5 (5) Aug 28, 2015
credibility is gained by presenting FACTS backed by empirical evidence, NOT PSEUDOSCIENCE CREATIONIST IDEALS or opinion backed by your "say-so"


My credibility is not being questioned. The credibility of theorists is questioned because they failed to link atoms to ecosystems and implied that mutations somehow lead to the de novo creation of genes, which is required for ecological adaptation to occur in the context of the physiology of reproduction.

Young earth creationists reported that the physiology of reproduction is perturbed by viruses, which they linked to all pathology in all living genera via mutations. Until someone links viruses to something besides loss of function with experimental evidence of biologically-based cause and effect, the creationists appear to have predicted why the paradigm shift that began in 1985 will end all claims touted by pseudoscientists about mutations and the evolution of increasing organismal complexity.
JVK
1 / 5 (5) Aug 28, 2015
The stability of organized genomes in species from microbes to man is nutrient-dependent and pheromone controlled.

I don't know one serious scientist who has not yet realized that fact.

I detailed it in the context of a model and published the extension of our 1996 review of RNA-mediated cell type differentiation with examples of cause and effect.

See: Nutrient-dependent/pheromone-controlled adaptive evolution: a model. http://www.ncbi.n...24693353
Captain Stumpy
5 / 5 (4) Aug 28, 2015
My credibility is not being questioned
@jk
yes, it is, mostly because of your continued insistence that pseudoscience (creationism) be introduced as science, but also because you have a 100% FAIL rate when "interpreting" other studies
thus, you actually have absolutely NO credibility, especially here: mostly because you post PSEUDOSCIENCE and then try to pass it off as science
The credibility of theorists is questioned
no, it isn't
you are questioning the METHODOLOGY, or perhaps the STUDY
learn some science before posting, mensa boy
Young earth creationists reported
it doesn't matter WHAT they report, there is NO SCIENCE in the creationist movement
https://en.wikipe...Arkansas

also note, promoting YEC is what makes you a pseudoscience hack
they are trying to validate a religion, NOT DO SCIENCE
Until someone links
strawman argument
because YOU don't know, we are all stupid?
Captain Stumpy
5 / 5 (4) Aug 28, 2015
the creationists appear to have predicted
@jk
1- https://en.wikipe...Arkansas

there is NO science in your creationists movement

2- they can make ANY claim they want, but until there is evidence that is validated by multiple sources, it is simply conjecture, so it is argument from stupidity
will end all claims touted by pseudoscientists about mutations
you mean like YOUR claims? you claim to have a model that replaces Evolution, but requires the same methodology as Evolution, so that makes you:
1- an idiot
2- perjurer
3- promoting MUTATIONS
4- a liar

what next? you gonna tell everyone that they proved the earth is 6-10K yrs old?
how does that explain the trees that are older, then?
worse yet... how does that explain the Meteors that are older? or the other rocks?

QUIT SPREADING PSEUDOSCIENCE
JVK
1 / 5 (5) Aug 28, 2015
...it strikes me as obvious that evolution would make use of Entanglement.


How could EVOLUTION link entanglement from the light-induced de novo creation of nucleic acids to the de novo creation of genes that must be linked to increasing organismal complexity by the biophysically constrained chemistry of nutrient-dependent RNA-mediated protein folding chemistry?

Two epigenetic traps are obviously required. Are you claiming that evolution set both traps? If not, what did evolution do?
Captain Stumpy
5 / 5 (4) Aug 28, 2015
I detailed it in the context of a model ... Nutrient-dependent/pheromone-controlled adaptive evolution: a model
except that your MODEL is debunked : SEE: Criticisms of the nutrient-dependent pheromone-controlled evolutionary model
by: Andrew Jones, BA

http://www.ncbi.n...4049134/

do you know what that BA after the name means? it means he is EDUCATED in the field and tore apart your model with ACTUAL SCIENCE... not creationist belief, like you tout here

also note: you continually denigrate "mutations" as pathological, but YOUR MODEL USES THEM, therefore, you are NOT familiar with actual biology to the level you want people to think you are (obvious per your historical felonious claims)
JONES IS EDUCATED, whereas you failed out of college [self admitted]

why should we accept your PSEUDOSCIENCE when you can't produce evidence more powerful than Lenski? especially as you continually denigrate the man!
Captain Stumpy
5 / 5 (4) Aug 28, 2015
How could EVOLUTION link entanglement from the light-induced de novo creation of nucleic acids...
you know, before you start spouting off something this stupid, you should actually read what "entanglement" (AKA- Quantum Entanglement) means in physics
https://en.wikipe...nglement

wait... never mind! you don't believe in definitions! you even said
Only pseudoscientists try to do that with definitions
AND
Medical laboratory scientists are not taught to believe in definitions or in theories about evolution
would you like the LINKS to your own words too?
ROTFLMFAO
what did evolution do?
you should first learn what a "theory" is in SCIENCE
a well-substantiated explanation of some aspect of the natural world that is acquired through the scientific method and repeatedly tested and confirmed through observation and experimentation
https://en.wikipe...c_theory
JVK
1 / 5 (5) Aug 28, 2015
you should first learn what a "theory" is in SCIENCE


[W]hat Haldane, Fisher, Sewell Wright, Hardy, Weinberg et al. did was invent.... Evolution was defined as "changes in gene frequencies in natural populations." The accumulation of genetic mutations was touted to be enough to change one species to another.... Assumptions, made but not verified, were taught as fact. http://www.huffin...211.html

The moderators need to learn the difference between facts and the pseudoscientific nonsense of neo-Darwinian evolution. It's time they stop Captain Stumpy from destroying yet another of John Hewitt's accurate representations of facts that link quantum physics to quantum biology via quantum smell linked to quantum consciousness.

The moderators continue to let biologically uninformed science idiots mock the efforts of serious scientists to inform others about how physics and chemistry are linked to biology.
docile
Aug 28, 2015
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docile
Aug 28, 2015
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JVK
1 / 5 (5) Aug 28, 2015
Re:
the striking instinctive ability of many animals to sense/avoid the earthquakes at distance.


Can you place that into the context of mutations and evolution? If not, Captain Stumpy and others like him may not accept it.

I'll wait for your ideas to gain acceptance in the context of experimental evidence of biologically-based cause and effect that links ecological variation to ecological adaptation in all genera via nutrient-dependent DNA repair, and epigenetic links from quantum physics to quantum consciousness --even though the affect on behavior of animals that sense earthquakes at a distance is probably an unconscious affect linked to hormone-organized and hormone-activated behaviors.

Scientific method: Defend the integrity of physics http://www.nature...-1.16535
Vietvet
4.2 / 5 (5) Aug 28, 2015


The moderators continue to let biologically uninformed science idiots mock the efforts of serious scientists to inform others about how physics and chemistry are linked to biology.


They should start with young earth creationist cranks like JVK.
docile
Aug 28, 2015
This comment has been removed by a moderator.
JVK
1 / 5 (5) Aug 28, 2015
Which titles of which publications look nonsensical to you, "docile?" What titles are you comparing them to?

Nutrient-dependent/pheromone-controlled adaptive evolution: a model.
http://www.ncbi.n...24693353

See also:

Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems

http://figshare.c...s/994281
johnhew
1 / 5 (1) Aug 28, 2015
docile, I wouldn't be so quick to call interesting new ideas nonsense. Not sure myself about the effects of mag field or even MRI on coherence so I got Matthew's thoughts for you, although I do wish academics could address questions here about their work more directly:

I have thought a lot about this.

Several things - an external magnetic field
does *not* cause decoherence of nuclear spins.
The nuclear spins do precess around
the magnetic field (although, pairs of spins which are in a "singlet" - the key resource
of quantum processing - have zero net spin
and are completely blind to such fields).

And magnetic fields *do* have an effect on the brain.
There is TMS (trans-cranial magnetostimulation) as a treatment for depression.
More "direct" are reports/studies from subjects whose heads are moved through magnetic field gradients
of a tesla in strength - see the attached paper.
The reports of dizziness and other symptoms by subjects exposed to
con't......
johnhew
1 / 5 (1) Aug 28, 2015
con't...
time and spatially varying magnetic fields, on page 764,

``For example, in the highest exposure condition, a metallic taste (12 subjects) was most commonly reported followed by dizziness (six subjects), headache (five subjects) and nausea (one subject)"

are entirely consistent with what NMR physicists all tell me - when they were graduate students,
upon placing their heads near the NMR magnet they would feel dizzy.

This phenomena seems *very* hard to explain within standard neuron firing ideas
(the magnetic energy scales are *tiny*). So, the possibility of nuclear spin neural processing
might be required for explanation…

Cheers,

Occup Environ Med 2012; 69 759-66
docile
Aug 28, 2015
This comment has been removed by a moderator.
johnhew
1 / 5 (1) Aug 28, 2015
We will never 'discover' the mechanism of consciousness. That is something one man needs to invent.
docile
Aug 28, 2015
This comment has been removed by a moderator.
johnhew
1 / 5 (1) Aug 28, 2015
When real spikes collide, they don't annihilate as traditional neuroscience would have it: http://medicalxpr...nce.html
Some think that suggests a soliton-like pulse description:
http://medicalxpr...son.html
And there is even some fancy FRET fluorescence observational evidence for them:
http://phys.org/n...ane.html
docile
Aug 28, 2015
This comment has been removed by a moderator.
JVK
1 / 5 (5) Aug 28, 2015
...our digestion is also quantum - but it will probably impress no one.


Who do you think I'm trying to impress with details and examples that link atoms to ecosystems via metabolic networks and genetic networks that are epigenetically-effected in all living genera?

docile, I wouldn't be so quick to call interesting new ideas nonsense.


Thanks John. Obviously, he doesn't know that is what happened to Luca Turin before his work with Drosophila was extended to octopuses.

I claimed that chemical ecology links (1) ecological niche construction, (2) social niche construction, (3) neurogenic niche construction, and (4) socio-cognitive niche construction. That was exemplified in the context of octopus genome sequencing.

Why doesn't someone else offer an alternative model of genome organization in all genera?

Any biologically uninformed science idiot can dismiss my model -- as we have seen.
docile
Aug 28, 2015
This comment has been removed by a moderator.
JVK
1 / 5 (5) Aug 28, 2015
as such not interesting for me here.


You just dismissed John's other reports also. Why not simply admit you are not going to look at the experimental evidence that links the anti-entropic energy of nutrient-dependent microRNAs to biophysically constrained protein folding chemistry in the cell types of all individuals of all genera via the innate ability of the immune system to protect cell types from the accumulation of viral microRNAs linked to all pathology via cell adhesion?

Stop ignoring the evidence:

Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics
http://www.scienc...abstract
Reported as: Imaging techniques set new standard for super-resolution in live cells
http://phys.org/n...lls.html

See also: Lipid raft disruption by docosahexaenoic acid... http://www.ncbi.n...22749134
johnhew
1 / 5 (1) Aug 28, 2015
But between you and me, how much can we really extrapolate from studies done with pure lipid membranes to actual myelinated, microtubulated, and actinated protein-lipid nervy membranes?
JVK
1 / 5 (5) Aug 28, 2015
John Hewitt and other intelligent people may want to see what Sir Paul Nurse did with communication linked from nutrient uptake to the pulsatile secretion of gonadotropin releasing hormone via the insertion of a single nutrient-dependent achiral amino acid (glycine) in one decapeptide. He extended my model in:

Life, logic and information http://www.nature...24a.html

Excerpt: "Pulses of information sent along the telegraph generate a code for letters and as a consequence sentences can be communicated. This converts the same signalling pathway from a simple on/off switch to a device that can transfer, for example, the works of Shakespeare. (p. 426) It is likely that dynamics has been exploited more generally in the evolution of biological systems for signalling purposes, allowing the communication of more complex information."

The signaling pathway is nutrient-dependent and pheromone-controlled in all vertebrates.
docile
Aug 28, 2015
This comment has been removed by a moderator.
JVK
1 / 5 (5) Aug 28, 2015
how much can we really extrapolate from studies done with pure lipid membranes to actual myelinated, microtubulated, and actinated protein-lipid nervy membranes?


Thanks for asking. The extrapolation to everything else about the vertebrate physiology of nutrient-dependent reproduction from what was learned via the sequencing of the octopus genome links marine invertebrates and all crustaceans and all insects to all mammals via the conserved molecular mechanisms of RNA-mediated protein folding chemistry.

If you want to look at this only in humans during their life history transitions you must look at measures of luteinizing hormone that link GnRH pulse frequency and amplitude to myelination and to brain development in homosexuals, heterosexuals, and Stephen Hawking.

Global Epigenomic Reconfiguration During Mammalian Brain Development
http://www.scienc...abstract
JVK
1 / 5 (5) Aug 28, 2015
See also the molecular epigenetics section of our 1996 Hormones and Behavior review:
http://www.hawaii...ion.html

I'm sure that "docile" will dismiss it as irrelevant, too. But he is not going to tell us how he links microbes to man via the RNA-mediated links we established from the epigenetic landscape to the physical landscape of DNA in all genera. We started with sex differences in cell types, but our model was quickly extended to all cell type differences in all living genera.

That's why I mentioned Gene Robinson in the context of phosphorylation. (11 hours ago). Elekonich and Robinson (2000) extended our model of hormone-organized and hormone-activated behavior before other serious scientists extended it across species from microbes to man.

http://www.ncbi.n...10980296 cites Diamond et al., 1996.
JVK
1 / 5 (5) Aug 28, 2015
http://www.scienc...14004006 cites "Organizational and activational effects of hormones on insect behavior" and Kohl (2013) my review of RNA-mediated cell type differentiation via nutrient-dependent amino acid substitutions with examples from across species.

http://www.ncbi.n...24693353 Nutrient-dependent/pheromone-controlled adaptive evolution: a model.
Vietvet
5 / 5 (2) Aug 28, 2015
Paul Nurse

"Nurse has criticized potential Republican party candidates for the US presidential nomination for opposing the teaching of natural selection, stem cell research on cell lines from human embryos, and anthropogenic climate change, even partially blaming scientists for not speaking up.[30] He was alarmed that this could happen in the U.S., a world leader in science, "the home of Benjamin Franklin, Richard Feynman and Jim Watson."
https://en.wikipe...ul_Nurse

Vietvet
5 / 5 (2) Aug 28, 2015
"British geneticist and cell biologist Paul Nurse outlines the theory of natural selection, or so-called 'survival of the fittest' – a phrase coined by Herbert Spencer. This is an idea, central to biology, that all life evolves and that natural selection is a major mechanism. It is still extremely relevant to our present-day lives, and is still argued about. Meanwhile, kin selection – as proposed by Bill Hamilton and picked up by John Maynard Smith – can be relevant to altruism and even to morality. Our wish to protect our relatives could extend to every other living thing in the biosphere, given that all life is related by descent"

Paul Nurse on natural selection – video

http://www.thegua...on-video

JVK strikes out again.
Vietvet
5 / 5 (2) Aug 28, 2015
"You could have ended up, if a school was so minded, not to teach creationism in science but to discuss creationism as the basis of the origin of species in religious studies, and not talk about evolution in science studies. In that case, the only message would have been about creationism and the message about evolution by natural selection could have been completely lost."
http://www.thegua...inisters

Vietvet
5 / 5 (2) Aug 28, 2015
"Creationism and 'intelligent design' are not scientific theories, but they are portrayed as scientific theories by some religious fundamentalists who attempt to have their views promoted in publicly-funded schools. There should be enforceable statutory guidance that they may not be presented as scientific theories in any publicly-funded school of whatever type."

"An understanding of evolution is central to understanding all aspects of biology. The teaching of evolution should be included at both primary and secondary levels in the National Curriculum and in all schools."

"According to The Guardian the signatories include Richard Dawkins, Professor Colin Blakemore, theoretical physicist Jim Al-Khalili, and the president of the Royal Society, Sir Paul Nurse"

http://thesunday....l-nurse/

The creationist JVK stepped in it again.
Vietvet
5 / 5 (2) Aug 28, 2015
On Religious Belief
"It was during my time at secondary school that I abandoned religion. My mother was a Baptist, and as a young teenager I was also a committed believer. But I had real difficulties reconciling a literal belief in Genesis with evolution, and my attempts to accommodate the biblical account of creation by viewing it as a poetic metaphor suitable for an unsophisticated nomadic people was completely rejected by my church. I gradually slipped away from religion over several years and became an atheist or to be more philosophically correct, a sceptical agnostic."
http://abetterhop...ief.html

@JVK

You've made known your hatred of atheists, does that apply also to a " sceptical agnostic"?
JVK
1 / 5 (5) Aug 28, 2015
These two articles link what is currently known about biophysically constrained nutrient-dependent microRNAs and RNA-mediated protein folding chemistry, which link quantum physics to quantum biology and also link quantum smell to quantum consciousness via what is known about virus-perturbed protein folding and pathology.

http://dx.doi.org.../ncb3227
http://www.nature...668.html

No experimental evidence of biologically-based cause and effect suggests neural and morphological novelties evolved in any invertebrate or vertebrate. All model organisms attest to how ecological variation is linked to ecological adaptation via RNA-mediated events.

If you are unable to link microRNAs and adhesion molecules to cell type differentiation, wait for someone else to explain it in a way you can understand.

Stop waiting for theorists / pseudoscientists to explain how anything is linked to biologically-based cause and effect.
JVK
1 / 5 (5) Aug 29, 2015
http://medicalxpr...nal.html
Excerpt: "...we discovered that glial cells have the ability to release membrane structural lipids in specific patterns that can then control axon migration and neuron organization."

Glycerophospholipid regulation of modality-specific sensory axon guidance in spinal cord.
www.sciencemag.or....aab3516

No matter what any biologically uniformed science idiot tells you, cell type differentiation is biophysically constrained by nutrient-dependent RNA-mediated protein folding chemistry that involves glucose and phosphorylation. That's why Israeli middle schools now teach evolutionary theory in middle schools. They want students to learn the difference between pseudoscientific nonsense and what is known about ecology so they can become serious scientists.

http://www.educat...olution/
Vietvet
5 / 5 (2) Aug 29, 2015
John Hewitt and other intelligent people may want to see what Sir Paul Nurse did with communication linked from nutrient uptake to the pulsatile secretion of gonadotropin releasing hormone via the insertion of a single nutrient-dependent achiral amino acid (glycine) in one decapeptide. He extended my model in:

Life, logic and information http://www.nature...24a.html

How could Paul Nurse extend your model when you reject common descent and that is a cornerstone of his science?
JVK
1 / 5 (4) Aug 29, 2015
Like everyone else who has linked what is known to serious scientists about cell type differentiation via the conserved molecular mechanisms of biophysically constrained RNA-mediated protein folding chemistry, Sir Paul Nurse extended my model to vertebrates with an accurate representation of how GnRH pulse frequency and amplitude integrate all signals from all other neuronal systems to change morphological and behavioral phenotypes during their experience-dependent development.

For an accurate representation of what goes wrong when viral microRNAs perturb cell type differentiation, see: http://www.longev...-normal.

...you reject common descent and that is a cornerstone of his science?


You don't understand the difference between theory and science. GnRH is the cornerstone of my model, which integrates the science of quantum physics and quantum biology.
Vietvet
5 / 5 (2) Aug 29, 2015


...you reject common descent and that is a cornerstone of his science?


You don't understand the difference between theory and science. GnRH is the cornerstone of my model, which integrates the science of quantum physics and quantum biology.

So you're suggesting Paul Nurse is a scientific idiot because he doesn't agree with you?
JVK
1 / 5 (4) Aug 29, 2015
Sir Paul Nurse once introduced Denis Noble, who coauthored this review with George Ellis and Timothy O'Connor http://rsfs.royal...abstract

George Ellis co-authored with Stephen Hawking in the late 60's. Stephen Hawking and Sir Paul Nurse have never indicated that they understand how quantum physics must be linked to quantum biology in any explanation of what is currently understood about how top-down causation links the sun's biological energy from its anti-entropic effects on RNA-mediated cell type differentiation to all biomass.

you're suggesting Paul Nurse is a scientific idiot because he doesn't agree with you?


I don't care who agrees with me because the facts known to serious scientists have not changed. Biologically uninformed science idiots are people who have never examined the facts that link quantum physics to quantum biology and instead use de Vries definition of "mutation" in their ridiculous theories.
Vietvet
5 / 5 (2) Aug 29, 2015
@JVK

It must be lonely belonging to a club of one.
johnhew
3 / 5 (2) Aug 29, 2015
Everybody who is anybody got to have tubulins, and microtubules, even mollusks. and when invertebrates need to myelinate, they have some of the most diverse and elaborate mechanisms around, from earthworms to Caridean shrimp to copepods: http://medicalxpr...ity.html
JVK
1 / 5 (4) Aug 29, 2015
Thanks, John Hewitt. Can you imagine what would happen if that fact was discussed in the context of nutrient-dependent pheromone-controlled de novo gene creation and ecological speciation from C. elegans to P. pacificus, and GnRH/estrogen receptor mediation of morphological and behavioral traits in white - throated sparrows with clear differences that appear to be due to uniparental or biparental feeding in the same species?

See also: Opinion: Engineering the Epigenome http://www.the-sc...igenome/

Note, the antagonists here have not yet recognized that some people still make claims about the "genome" at the time when serious scientists have learned how to discuss the epigenome, which requires them to abandon ridiculous theories that do not link physics and chemistry to biology via molecular epigenetics.

Steven Taylor (aka Vietvet) assumes Sir Paul Nurse's claims are evidence based.
JVK
1 / 5 (5) Aug 29, 2015
Advancing precision medicine through multi-omics: An integrated approach to tumor profiling
Excerpt: "During the webinar, the speakers will:
Discuss how analyzing multi-omics data, such as copy number alteration and coding and noncoding RNA expression, can lead to more rapid identification and prioritization of cancer driver events."

My comment: These are RNA-mediated events that the Mayo Clinic in Florida just linked from microRNAs to adhesion proteins and cell type differentiation in the context of pathology. The sequencing of the octopus genome linked microRNAs to adhesion proteins and cell type differentiation in healthy longevity in all genera via their physiology of nutrient-dependent reproduction.

"Hear the experts discuss how a multi-omics approach to cancer research can advance our understanding of cancer biology and uncover new biomarkers.
Register TODAY: webinar.sciencemag.org / Produced by the Science/AAAS Custom Publishing Office."
Captain Stumpy
5 / 5 (2) Aug 30, 2015
Biologically uninformed science idiots are people who have never examined the facts that link quantum physics to quantum biology and instead use de Vries definition of "mutation" in their ridiculous theories
@jk
you mean like your claims to have
In the past two years I've learned enough about physics to link the speed of light on contact with water to the de novo creation of amino acids
you still haven't produced evidence for this...
plus there is the whole blatant lie at the end of your BS post ... maybe you can get john to explain the actual biological definition of "mutation" (in very small words) as used by biologists/medicine today since you seem to be unable to read any of the links i've given you historically
By the way, deVries definition is NOT the same as the modern definition
they didn't know anything about DNA

https://en.wikipe...n_theory

WHY do you continue to post this lie?
Captain Stumpy
5 / 5 (2) Aug 30, 2015
Biologically uninformed science idiots are people who have never examined the facts
lets examine this a bit!

jk says we use deVries definition of mutation (link in last post)

definition modern biologists use: https://en.wikipe...Mutation

FACTS: jk IGNORES the definition to promote pseudoscience and his personal creationist agenda
OOPSIE

jk says
Mutations perturb protein folding
http://medicalxpr...mic.html

fact: beneficial mutations exist
https://en.wikipe...Mutation#Beneficial_mutations

http://myxo.css.m...dex.html

FACT: jk's model REQUIRES mutations [shall i re-post that whole conversation again, mensa boy?]

OOPSIE AGAIN

the point is?
jk is a
Biologically uninformed science idiot who has never examined the facts
who is promoting his creationist dogma over science
https://en.wikipe...Arkansas

jk=PSEUDOSCIENCE
totinen
not rated yet Aug 30, 2015
Lithium-6 isotope spin is 1, not 1/2.
kochevnik
5 / 5 (2) Aug 30, 2015
Sad to see physorg still tolerates prodigious quantities of magical thinking to be posted on a science site
johnhew
1 / 5 (1) Aug 30, 2015
Captain, I have given an account of mutation at least once here, problem is one Eskimo's mutation is another Saharan's adaptation:
http://medicalxpr...bad.html
johnhew
3 / 5 (2) Aug 30, 2015
totinen, I hope you are considerably more knowledgeable than me regarding that, and can clarify the issue, because all I can really do is ask Google who tells me there is more to it than your singular statement and that Lith-6 is considered spin 1/2
http://triton.iqf.../Li.html
JVK
1 / 5 (4) Aug 30, 2015
Thanks for the reminder and link to your post on mitochondrial DNA mutations, John Hewitt, where Andrew Jones, (aka anonymous_9001) wrote:

Mutagenesis studies irrefutably show mutations having beneficial effects on enzymes.


The beneficial effects can now be linked to "re-evolution" of the bacterial flagellum in 4 days and/or the light-activated differentiation of mouse embryonic stem cells into neurons in 4 days.

http://www.ucsf.e...em_cells

Excerpt: "He imagines a day when researchers can illuminate a bath of undifferentiated stem cells with a pattern of different colors of light and come back the next day to find a complex pattern of blood and nerve and liver tissue forming an organ that can be transplanted into a patient."

Who will be first physicist, chemist, or evolutionary theorist to explain this?

JVK
1 / 5 (4) Aug 30, 2015
Sad to see physorg still tolerates prodigious quantities of magical thinking to be posted on a science site


Agreed. Each time John Hewitt accurately represents what is known about the link from quantum physics to quantum biology, the biologically uninformed science idiots attack and claim that their ridiculous theories about mutations and evolution make sense.

John should not need to repeat his claim that
...one Eskimo's mutation is another Saharan's adaptation


Biologically uninformed science idiots should learn the difference between a mutation and nutrient-dependent RNA-mediated amino acid substitutions, which links gene duplication to fixation of amino acid substitutions via the physiology of reproduction and cell type differentiation of all cells in all individuals of all living genera in as few as 4 days (from ES cells to neurons) or "re-evolution" of the bacterial flagellum.

Why haven't moderators stopped the theoretical nonsense?
Captain Stumpy
5 / 5 (2) Aug 30, 2015
Captain, I have given an account of mutation at least once here
@John
thanks. my problem
The word 'mutation' is often associated with something negative
this is only typical in the uneducated and layman. in biology/medicine, it tends to have a very specific meaning, correct?
that can be read here: https://en.wikipe...Mutation

it is accurate, & reflects the lexicon as used by NIH, etc, so there is no need to continue to re-link various dictionaries from schools or orgs to demonstrate this

now... jk makes a few broad statements
Mutations perturb protein folding
http://medicalxpr...mic.html

or
Mutations have always been linked from perturbed protein folding to pathology
http://phys.org/n...ete.html

nice broad sweeping all-encompassing statements...
2Bcont'd
Captain Stumpy
5 / 5 (2) Aug 30, 2015
@John Cont'd
but are they backed by scientific evidence?
you should well know that they are not: From the following http://myxo.css.m...dex.html

to various other studies: http://www.extavourlab.com/

you can also see this supported at the following site: http://beacon-center.org/

if you actually read the scientific literature, you will see that there IS beneficial mutations... and that is proven by experimental evidence that has been validated. that is not a claim, supposition, conjecture nor belief in any way
it is EVIDENCE

now, what this tells us is: jk is trying to redefine the word or term based upon personal information that is conflicting with scientific data
why conflicting? look above
the creationists appear to have predicted...
jk posts creationist diatribe religiously on PO (intentional use of the word, BTW)
plus, we can see by other claims made, that jk is promoting a fallacy and doesn't have evidence
2Bcont'd
Captain Stumpy
5 / 5 (2) Aug 30, 2015
@John cont'd
case in point, his recent claims
In the past two years I've learned enough about physics to link the speed of light on contact with water to the de novo creation of amino acids...
Where is the evidence of this?
with your background, surely you know (or, at least recognize) that this claim would be an instant Nobel winning study, right?

but lets look at more: his rna-mediated site he links to!
the site mixes creationist religious propaganda with actual science... if you are trying to convince the world by evidence, you do NOT push or promote PSEUDOSCIENCE in your work - you push the evidence

jk historically also claimed a felonious experience as a diagnostician - http://phys.org/n...nes.html

this requires a license ... how many historical licenses have been given to non-degree holding people? lets be generous: include the dates to 1940

2Bcont'd
Captain Stumpy
5 / 5 (2) Aug 30, 2015
@John
what i am getting at is that jk is not only an unreliable spamming trolling poster, but that his credibility is absolutely shot

you make an argument with evidence in your link... however, it doesn't appear to me that you've actually said that the definition of "mutation" is in any way threatened by the evidence you provided. not the common use of the word... but the actual definition as used by professionals who need to convey a specific message: like biologists and medical pro's

what you have done, IMHO, is open up a new perspective and means to view evidence. this is how science actually works, BTW... not by arbitrary redefining based upon religious dogma

where is jk's evidence that there are no beneficial mutations? and why can't he refute Lenski or any other study that has been validated? you speak of nuances, jk speaks in absolutes... something atypical for science (measurements are even within limitations of the measuring device, right?)
2Bcont'd
Captain Stumpy
5 / 5 (2) Aug 30, 2015
@John
finally - the overwhelming conclusion one gets from reading jk is that he is simply here to proselytize a religious perspective that has been demonstrated, with EMPIRICAL EVIDENCE, to have no scientific basis - see: https://en.wikipe...Arkansas

i don't care what you want to call it, or how you want to nuance that... that is, was, and always shall be considered PSEUDOSCIENCE

now, that is not to say he has not made any contributions. however, being right one time does NOT justify any "argument from authority" as thrown around by jk
PERIOD

especially when there is no evidenciary support

also- supporting factual arguments are one thing, but when someone uses repetitious rhetoric that is known to be fallacious, like jk, it undermines not only HIS credibility, but also the supporters of said diatribes, especially when he denigrates entire disciplines of science because of his belief

take that into consideration, please
Captain Stumpy
5 / 5 (2) Aug 30, 2015
Why haven't moderators stopped the theoretical nonsense?
because you are being protected by the moderators!
otherwise you would have been banned a long time ago
By all means, please show how Lenski's work (or Extavour, or Whittaker, etc) is debunked and that mutations are never beneficial and are always pathological, as you've claimed historically
Please demonstrate how all of the above mentioned, and their labs/workers educated in biology, medicine etc are "Biologically uninformed science idiots" as you so frequently (and libelously)have claimed

by all means: i agree! your rhetoric should be deleted and banned!

there is NO science in the creationist movement
that is even evident to the courts!
perhaps you should reconsider your affiliations, mensa boy
(of course, i also suggest reading and comprehension courses as well- considering your track record to date
try hooked on phonics!)
Captain Stumpy
5 / 5 (2) Aug 30, 2015
I have given an account of mutation...problem is one Eskimo's mutation is another Saharan's adaptation:
http://medicalxpr...bad.html

@JohnHew
POST SCRIPT

perhaps you would like to explain, in detail that laymen can understand, just how exactly is your link showing that the definition of mutation (as used by Biologists, etc, seen here: https://en.wikipe...Mutation )...just how exactly has it compromised or invalidated the term considering your link?

how, exactly, does your link show the redefining of the term? or that the term is not precise?

Please be explicit, and break it down clearly for the laymen on the site... and try not to use jargon or terms unless you specifically link a definition for clarity!

THANKS
JVK
1 / 5 (5) Aug 30, 2015
John Hewitt's specialized interest may not be allow him to link quantum physics to quantum biology. in a context that might be accepted by biologically uninformed science idiots. Thus, before Captain Stumpy again puts an end to any intelligent discussion of cause and effect, I will add this:

Evolutionary theorists have claimed "...it is natural selection that chooses some genes rather than others and in so doing orchestrates the interaction between the two inheritances so that high degrees of recurrent functional order can emerge and persist, such as eyes or maternal love." -- http://www.ncbi.n...14599284

They appear to believe that natural selection is contextually comparable to claims about the anti-entropic force of the sun's biological energy.

In the context of virus-perturbed protein folding, natural selection is linked to the evolution of monogamy in prairie voles and human love by Larry Young. See: https://www.youtu...04x6MvMY
JVK
1 / 5 (5) Aug 30, 2015
Re:
natural selection is linked to the evolution of ... human love


The post-genomic era includes what serious scientists have detailed in the context of biophysically constrained nutrient-dependent RNA-mediated protein folding. They link microRNAs and adhesion proteins to cell type differentiation in all cells of all individuals of all living genera. They link viruses to pathology via the conserved mechanisms of molecular epigenetics , and I linked atoms to ecosystems via the physiology of reproduction.

I answered the question: "...how is it that living collections of atoms are drawn from that even more immensely minute subset of ordered arrangements that reliably construct new systems that duplicate the functional order in the parent physical systems..." asked in http://www.cep.uc...iter.pdf

http://figshare.c...s/994281

What's left?
JVK
1 / 5 (5) Aug 30, 2015
Re: What's left?

Evolutionary theorists have never presented experimental evidence of biologically-based cause and effect that links quantum physics to quantum biology, or that links mutations to the evolution of a new species via the biophysically constrained chemistry of nutrient-dependent RNA-mediated protein folding.

What's left is for them to explain themselves in terms that serious scientists can put into the context of what is known about cell type differentiation, which obviously requires the anti-entropic epigenetic effects of nutrient-energy. That fact can be placed into the context of Darwin's "conditions of life."

This ridiculous claim can be placed into that same context: "Selection built anti-entropic mechanisms into organisms to orchestrate transactions with environments so that they have some chance of being organization-building and reproduction-enhancing rather than disordering."
http://www.ncbi.n...14599284
JVK
1 / 5 (3) Aug 30, 2015
http://www.washin...ory.html

Excerpt: "The Internet started as a bastion for free expression. It encouraged broad engagement and a diversity of ideas. Over time, however, that openness has enabled the harassment of people for their views, experiences, appearances or demographic backgrounds. Balancing free expression with privacy and the protection of participants has always been a challenge for open-content platforms on the Internet. But that balancing act is getting harder. The trolls are winning."

Also, see what happened when PZ Myers was confronted with his own ignorance of cell type differentiation, with representations of what is known about biophysically constrained protein folding chemistry.

http://scienceblo...-aliens/

New comments have been temporarily disabled. Please check back soon
JVK
1 / 5 (4) Aug 31, 2015
Please demonstrate how all of the above mentioned, and their labs/workers educated in biology, medicine etc are "Biologically uninformed science idiots" as you so frequently (and libelously) have claimed


Many have failed to link virus-driven cell type differentiation from Strep species to Staph species and to enteric pathogens like specific strains of E.coli via thermodynamic cycles of protein biosynthesis and degradation linked to the stability of organized genomes in species from microbes to man via single amino acid substitutions, which are also linked to the prevention of cancer in specific tissues.

What's worst is that after Koonin admitted the role of viruses was not included in the Modern Synthesis, he seems to still be pretending he does not known enough about RNA-mediated cell type differentiation to link the viruses to the amino acid substitutions that differentiate different species of bacteria. See: http://dx.doi.org...ure14299
Vietvet
5 / 5 (1) Aug 31, 2015
James V. Kohl

Northern Geogia
August 27, 2015
"The problem for atheists becomes bigger almost every day."

Where is PZ Myers, when we need to learn more about cell type differentiation via mutations, now that all serious scientists have abandoned that pseudoscientific nonsense because they have learned about biologically-based cause and effect?

See for example: DNA methylation pathways and their crosstalk with histone methylation http://dx.doi.org...nrm4043"

Why isn't little PeeZee slamming down the creationists now that they reported the link from virus-driven entropic elasticity to genomic entropy?
http://scienceblo...-aliens/

"The problem for atheists becomes bigger almost every day."

That's it in a nutshell. JVK's world view is based on creationism, scientific evidence be damned.

And why just atheists, why not theological evolutionists like Francis Collins and Dobzhansky and many others?
Vietvet
5 / 5 (1) Aug 31, 2015
Everything JVK writes has to be seen in the context of his deep belief in creationism, that comes first and he tortures science to fit that belief.
JVK
1 / 5 (4) Aug 31, 2015
...has to be seen in the context of his deep belief in creationism...


No. It must be seen in the "light of evolution" that eclipsed the light of the sun as if it were a permanently placed moon and the sun revolved around the earth.

...why just atheists, why not theological evolutionists like Francis Collins and Dobzhansky and many others?


Collins supports the change from theistic evolution to personalized medicine that includes what Dobzhansky claimed about nutrient-dependent pheromone-controlled RNA-mediated cell type differentiation in primates: "... the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla. ( p. 127)" http://img.signal...nsky.pdf

Why do you think little PeeZee Myers banned me from discussion of chromosomal rearrangements and blocked any further posts... cont.
JVK
1 / 5 (4) Aug 31, 2015
...cont.

about the links from virus-driven entropic elasticity to genomic entropy?

See also: http://blogs.plos...esa-100/

Myers and other biologically uninformed science idiots like him have been forced to look at the "dark side of the moon" where the "light of evolution" has not been blocked by pseudoscientists touting nonsense. Only anonymous fools continue to ask questions about what is known to creationists and try to pit what is known by pseudoscientists against knowledge of cell type differentiation that links all genera via the conserved molecular mechanisms of biophysically constrained RNA-mediated protein folding chemistry, which links light and the physiology of reproduction to all the earth's biomass.

When little PZ returns from the dark side of the moon, he may tell us why no evidence of evolved life has been found, or simply ignore that fact.
Vietvet
5 / 5 (1) Aug 31, 2015

Collins supports the change from theistic evolution to personalized medicine that includes what Dobzhansky claimed about nutrient-dependent pheromone-controlled RNA-mediated cell type differentiation in primates:

Unsupported claims.
JVK
1 / 5 (4) Aug 31, 2015
...he tortures science to fit that belief.


Science has been tortured by evolutionary theorists who tried to make their ridiculous theories about mutations fit into the context of Darwin's 'conditions of life." The end of the nonsense should have come when theorists claimed that natural selection linked some unknown form of anti-entropy via mutations to evolution. But, as we have seen here, the trolls like to believe in such nonsense and they ignore what is known to serious scientists.

See for example: https://www.faceb...ediated/ or
http://www.the-sc...st122986

If the link from the sun's biological energy to the phytochemical is not clear, I'll see you on the "dark side of the moon."
Vietvet
5 / 5 (2) Aug 31, 2015
15 Answers to Creationist Nonsense
"Opponents of evolution want to make a place for creationism by tearing down real science, but their arguments don't hold up"
http://www.scient...tionist/

JVK
1 / 5 (4) Aug 31, 2015
http://www.scienc...5724.htm
Discovered: Tiny drops of 'perfect' fluid that existed in the early universe

Excerpt: Additional experiments confirmed that this liquid is indeed composed of visible matter's most fundamental building blocks, quarks and gluons, and that the flow occurs with minimal resistance -- making it a nearly "perfect" liquid plasma.

My comment: If I were a theoretical physicist, I would either put this into some meaningful context linked to the biologically-based creation of nucleic acids and RNA-mediated cell types, or claim that cells and cell type differences evolved from the primordial soup I cooked up in an earlier theory that linked random events to the creation of a 'perfect' fluid.

What do other serious scientists do, for comparison?
JVK
1 / 5 (4) Aug 31, 2015
Opponents of evolution...


are opposed to the pseudoscientific nonsense touted by neo-Darwinian theorists who invented their theories based on de Vries definition of mutation and assumptions about how long it would take for an accumulation of mutations to lead to the evolution of a new species via natural selection, which was placed into the context of anti-entropy.

The anti-entropic energy of the sun was not considered to be sufficient to prevent virus-driven entropic elasticity from becoming genomic entropy because neo-Darwinists ignored Darwin's 'conditions of life,' which are nutrient-dependent and controlled by the physiology of reproduction in all genera.

If you ignore Darwin's 'conditions of life' but claim to be an evolutionary theorist or evolutionary biologist, others will claim that you are a biologically uninformed science idiot.
JVK
1 / 5 (4) Sep 01, 2015
John Hewitt,

The trolls destroyed another attempt to discuss what is known to serious scientists at the same time I was alerted to a connection from soil bacteria to "... plant-derived phenolics (14), which are known to function as modulators of DNA methylation, intracellular signaling networks, chromatin structure, and microRNA (15, 16)." http://advances.s...e1500795 -- reported as: http://www.the-sc...en-Bees/

Again, this appears to link Luca Turin's works from quantum physics to quantum biology with an example from a model organism. The honeybee links the nutrient-dependent RNA-mediated chemistry of biophysically constrained protein folding across species via the physiology of reproduction.

The question remains: What is the origin of phenols?
Captain Stumpy
5 / 5 (1) Sep 01, 2015
No. It must be seen in the "light of evolution"
Wrong again
1- it is the THEORY of EVOLUTION - and if you had any inkling what a scientific theory entailed, you would understand that the theory is based upon empirical evidence
2- your "model" is called a hypothesis AT BEST, but considering the holes pointed out by Jones, it is a failed one and thus falsified and considered debunked
3- the rest of that sentence is STUPID and irrelevant ... it doesn't even make a good analogy, especially since there is NO science in the creationist movement: https://en.wikipe...Arkansas

that is called empirical evidence... in court, it was called proof!
so we can call it PROOF that you push PSEUDOSCIENCE

especially as long as you promote creationist dogma and continue to mix it with science on your personal pages OR promote it here as validated science

[validated]
that is another term you should look up re: scientific method
Captain Stumpy
5 / 5 (1) Sep 01, 2015
https://www.faceb...ediated/ or
!- facebook is NOT a reputable science journal with peer review (neither is Youtube)
2- reported for PSEUDOSCIENCE
John Hewitt,
The trolls destroyed another attempt to discuss what is known to serious scientists
appealing to John for protection? you ARE correct... the trolls destroyed the thread. problem is, YOU are the TROLL, pushing creationist diatribe and PSEUDOSCIENCE

this is a science site, not a creationist or religious forum
Again, this appears to link Luca Turin's works from quantum physics to quantum biology
you're going to have to be more specific... the author doesn't understand what you are trying to say and thinks you are confused

bee specific about your claims [intentional] so the author can either refute or accept your proposal/suggestion because you aren't making sense

PS
where is your evidence about linking the speed of light to etc etc etc????
JVK
1 / 5 (4) Sep 01, 2015
http://medicalxpr...ode.html

As all serious scientists know, the de novo creation of olfactory receptor genes links quantum physics to quantum biology via Luca Turin's quantum smell, which is linked to quantum consciousness by experimental evidence of anesthesia-induced epigentic changes in neuronal cell type signaling in flies and octopuses.

See also:
http://perfumingt...r-genes/

Excerpt: Is there one evolutionary theorist who will accept the facts known to serious scientists about the odor-induced de novo creation of olfactory receptor genes?

See also:

See also: An Epigenetic Trap Stabilizes Singular Olfactory Receptor Expression

My comment: The epigenetic trap is nutrient-dependent and controlled by the physiology of reproduction. See for examples: Nutrient-dependent/pheromone-controlled adaptive evolution: a model.
totinen
1 / 5 (1) Sep 02, 2015
totinen, I hope you are considerably more knowledgeable than me regarding that, and can clarify the issue, because all I can really do is ask Google who tells me there is more to it than your singular statement and that Lith-6 is considered spin 1/2
http://triton.iqf.../Li.html


Ok, thanks
JVK
1 / 5 (3) Sep 04, 2015
PS
....evidence about linking the speed of light to etc etc etc????


See Schrodinger, Dobzhansky and see Stuart Kauffman et al: Quantum Criticality at the Origin of Life
http://arxiv.org/...02.06880

Google may not be the best source of information for those who are interested in linking quantum physics from chemistry to quantum biology via protein folding without including the magic of neo-Darwinian theory.

Excerpt: "The conclusions stated above are subject to the limitations of statistical inference, but correlations of this magnitude with all 190 amino acid pairs cannot be due to chance." http://www.scienc...abstract

Neo-Darwinists took their ridiculous statistical inferences and substituted them for what is known about biologically-based nutrient-dependent cause and effect, which is biophysically constrained via thermodynamic cycles of protein biosynthesis and degradation in the context of the physiology of reproduction.
victoryengineer
3 / 5 (2) Sep 16, 2015
JVK,
Enough is enough already. Please take your pseudoscience bullshit and go away. This is a science site that has nothing to do with your quackery. There are surely web sites that foster your kind of nonsense where you would be welcomed. Please go there and quit wasting our time and yours.
JVK
1 / 5 (3) Sep 16, 2015
This is a science site that has nothing to do with your quackery.


See also: Periodic Scarred States in Open Quantum Dots as Evidence of Quantum Darwinism http://link.aps.o...4.176801

It was reported here as: New evidence for quantum Darwinism found in quantum dots
http://phys.org/n...808.html

This is a science site that has nothing to do with your quackery.


Perhaps "victoryengineer" is another anonymous biologically uninformed science idiot cannot connect the dots.

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