Related topics: genes · embryos

Flaws emerge in modeling human genetic diseases in animals

My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical that fish biology has any relevance ...

Fungal compound inhibits important group of proteins

Researchers in the group of Jeroen den Hertog, in collaboration with researchers in Leiden, have found that a compound inhibits a group of proteins called BMP receptors. This compound, called cercosporamide, was previously ...

Social experiences impact zebrafish from an early age

It is commonly said that childhood experiences shape adult behavior; that events that we may not even remember can have long-lasting or even permanent effects. In a new article by scientists at the Champalimaud Center for ...

How mutant zebrafish helped unlock the secret to their stripes

Zebrafish are one of the most well studied animals on the planet. But how they came by their beautiful black and gold stripes is more of a mystery. Our new research used mathematical modeling—and detailed observations of ...

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